Примери за използване на Cytotoxic activity на Английски и техните преводи на Български
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Cytotoxic activity in cell cultures.
Turmeric has a pronounced cytotoxic activity against the 16 and 18 genotypes of HPV.
In addition, IL-18 induces production of cytokines and increases cytotoxic activity of lymphocytes.
Enhance the cytotoxic activity of anticancer drugs;
Studies have found this herb to possess antibacterial, anti-malarial, anti-trypanosomal, antidiabetic,anti-inflammatory and cytotoxic activity.
These cells have no cytotoxic activity and do not kill infected cells or clear pathogens directly.
For example, in the blood compatibility test for non hemolytic, cytotoxic activity in vitro experiments for non-toxic.
Cytotoxic activity of alkylating agents in the presence of centrophenoxine and its hydrolysis products. Sladek NE.
In non-clinical studies,venetoclax has demonstrated cytotoxic activity in tumour cells that overexpress BCL-2.
Cytotoxic activity in cell cultures Gemcitabine shows significant cytotoxic effects against a variety of cultured murine and human tumour cells.
It is believed that natural TNF released in the body has a greater cytotoxic activity and less toxic effects than recombinant TNF.
The cytotoxic activity of trifluridine/tipiracil hydrochloride against several human tumour xenografts correlated highly with the amount of trifluridine incorporated into DNA, suggesting this as the primary mechanism of action.
There are some polyimide has good biological compatibility, for example,in the blood compatibility test for non hemolytic, cytotoxic activity in vitro experiments for non-toxic.
The cocrystals of kojic acid with quercetin were found to have two times better cytotoxic activity to human cervical cancer cells(HeLa) and human colon cancer cells(Caco-2) in comparison with quercetin itself.
Monomethyl auristatin E powder(MMAE powder) is efficiently released from SGN-35 within CD30+ cancer cells and,due to its membrane permeability, is able to exert cytotoxic activity on bystander cells.
Daunorubicin has antimitotic and cytotoxic activity, which is achieved by forming complexes with DNA, inhibiting topoisomerase II activity, inhibiting DNA polymerase activity, affecting regulation of gene expression, and producing DNA-damaging free radicals.
Polysaccharide fractions isolated from P. linteus were found to be related to the increased activity of immune cells such as the production of cytokines by macrophages andB-cells or the increased cytotoxic activity of natural killer cells.
The study was conducted on a graviola seed where the fractionation obtained compounds, one of which,(cis- annonacin),had a selective cytotoxic activity on cancer cells of the colon, and it was 10,000 times stronger than the pharmaceutical drug adriamycin.
Engagement of PD-1 with its ligands PD-L1 and PD-L2, which are expressed by antigen presenting cells and may be expressed by tumour cells and/or other cells in the tumour microenvironment, results in inhibition of T cell function such as proliferation,cytokine secretion, and cytotoxic activity.
The data assessed during the Art.31 referral procedure in 2011 regarded the carcinogenic potential of dexrazoxane due its cytotoxic activity and on the occurrence of second malignant neoplasms in the paediatric population; such data justified the introduction of a contraindication of the product in children aged 0 to 18 years.
By binding to its receptors,PD-L1 reduces cytotoxic T-cell activity, proliferation and cytokine production.
Binding of PD-L1 to the PD-1 and B7.1 receptors found on T-cells andantigen presenting cells suppresses cytotoxic T-cell activity, T-cell proliferation and cytokine production.
The medication is able to stimulate the functional(cytotoxic and bactericidal) activity of macrophages and neutrophils, enhance the proliferation of B and T lymphocytes, and enhance the synthesis of specific antibodies.
On one hand,their carbamoylating activity was reported to contribute to the cytotoxic properties of their parent drugs by inhibiting DNA repair enzymes.
An older 2011 in vitro(test tube) study reported in the Internal Journal of Toxicology indicated that peppermint had cytotoxic(“cyto” means cell) activity.
To assess for the presence of neutralising antibodies,samples from 29 patients with confirmed binding activity to the modified cytotoxic T-lymphocyte-associated antigen 4(CTLA-4) region of the molecule were assessed by an in vitro assay; 8(27.6%) patients were shown to possess neutralising antibodies.
According to this study by the Department of Agricultural Sciences of the Aarhus University of Denmark,“polyacetylenes have shown many interesting bioactivities including anti-inflammatory,antiplatelet-aggregatory, cytotoxic, antitumor activity, as well as activity against bacteria and mycoplasma.”.
According to this study by the Department of Agricultural Sciences of the Aarhus University of Denmark,“polyacetylenes have shown many interesting bioactivities including anti-inflammatory,antiplatelet-aggregatory, cytotoxic, antitumor activity, as well as activity against bacteria and mycoplasma.”.
Cytotoxic T-lymphocyte antigen-4(CTLA-4) is a key regulator of T-cell activity.
Inhibition of protein synthesis secondary to the asparaginase-induced depletion of asparagine has been shown to attenuate the cytotoxic effect of MTX which requires cell replication for its antineoplastic activity.