Примери за използване на Environmental compartments на Английски и техните преводи на Български
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Medicine
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Ecclesiastic
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Ecclesiastic
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The level of accumulation and time dependency for the different environmental compartments were evaluated.
Likely pathways to environmental compartments and potential for adsorption/desorption and degradation.
The concentrations of additives(or metabolites) producing serious adverse effects for various trophic levels in the environmental compartments of concern shall be determined.
The CVMP recommended obtaining samples from relevant environmental compartments after use of the 5 mg/ml pour-on solution or 100 mg/ml injectable solution in beef cattle on pasture.
The exposure assessment should ideallyhave addressed this and considered a realistic worst-case situation with respect to the respective receiving environmental compartments.
In order to reduce the risk from the accumulation of zinc in environmental compartments, a number of RMMs are proposed to be included in the product information.
The risk management measures to reduce or avoid direct and indirect exposure of humans(including workers and consumers)and the different environmental compartments to the substance.
The duration and frequency of emissions of the substance to the different environmental compartments and sewage treatment systems and the dilution in the receiving environmental compartment. .
In addition, the overall environmental risk caused by the substance shall be reviewed by integrating the results for the overall releases, emissions andlosses from all sources to all environmental compartments.
The duration and frequency of emissions of the substance to the different environmental compartments and sewage treatment systems and the dilution in the receiving environmental compartment. .
The key aim of the study is a detailed analysis of the current state of the environment, identification of principal pollutants, their dynamics, transport processes, andtransformation among the various environmental compartments.
Due to accumulation of zinc risks have been identified for all environmental compartments, either immediately(sediment, some soil and surface water types) or delayed(other soil types, ground-, and surface waters).
Considering further PEC-refinement(FOCUS SW- calculations and excretion pattern evaluation for risk mitigation measures)the maximum PEC values for the relevant environmental compartments are summarised as follows.
The above risk mitigation measures will only delay the risks identified in all environmental compartments if manure from pigs treated with veterinary medicinal products containing zinc oxide is applied to land.
The Member State shall not authorise a biocidal product if the risk assessment confirms that the active substance, or any substance of concern, or any degradation, orreaction product presents an unacceptable risk in any of the environmental compartments, water(including sediment), soil and air.
The understanding of pollutants' behaviour in various environmental compartments, remediation of contaminated sites and evolution of ecosystems in the Earth's history are just a few examples of the topics.
The determination of the emissions, pathways and rates of movement of an active substance or a substance of concern in a biocidal product and its transformation or degradation in order to estimate the concentration/doses to which human populations,animals or environmental compartments are or may be exposed.
The CVMP considered that there is some uncertainty associated with the calculated risks for some environmental compartments and recommended various risk mitigation measures, which were anticipated to reduce the accumulation of zinc in the environment.
No matter which model and application rates are used, a risk to the environment is predicted(RQ≥ 1), andit will only be a matter of time before risks are present in all environmental compartments if manure from pigs treated with veterinary medicinal products containing zinc oxide is applied to land.
In particular it shall contain an estimation of the amounts of the substance released to the different environmental compartments during all activities carried out by the manufacturer or importer and all identified uses, and an identification of the likely routes by which humans and the environment are exposed to the substance.
Even applying the risk mitigation measures above it will only be a matter of time before risks are present in all environmental compartments if manure from pigs treated with veterinary medicinal products containing zinc oxide is applied to land.
Moreover, in view of the need for a targeted field study to generate data on the fate andbehaviour of moxidectin in different environmental compartments under actual use conditions and to verify that the likelihood of persistence, bioaccumulation and toxicity to occur in the environment is low, it is considered that conditions affecting the marketing authorisations should be imposed(see Annex IV).
The estimation of the incidence and severity of the adverse effects likely to occur in a human population,animals or environmental compartments due to actual or predicted exposure to any active substance or substance of concern in a biocidal product.
Where relevant, appropriate information on the persistence and multiplication of the micro-organism, in all environmental compartments has to be given,unless it can be justified that exposure of the particular environmental compartment to the micro-organism is unlikely to occur.
(4) of Directive 2001/82 for Gutal(EMEA/V/A/108),will only delay the risks identified in all environmental compartments if manure from pigs treated with veterinary medicinal products containing zinc oxide is applied to land.
In the frame of the aforementioned procedure, the Committee for Medicinal Products for Veterinary Use(CVMP)considered that there is some uncertainty associated with the calculated risks for some environmental compartments as the predicted environmental concentration(PEC) due to the use of zinc as a veterinary medicinal product could not be validated, and the predicted no effect concentration(PNEC) did not always account for zinc bioavailability(specifically for the sediment compartment). .
However, this measure would slow down the accumulation of zinc and, hence,reduce the risk for each environmental compartment.
If appropriate, the assessment proceeds to the second phase where the fate and effects of the product are determined anda risk assessment for the relevant environmental compartment is carried out.
The first tier, Phase IIA, makes use of a limited number of fate andeffect studies to produce a conservative assessment of risk based on exposure and effects in the environmental compartment of concern.
United Kingdom for zinc, and were used by the applicant to establish different PNECs for each environmental compartment. .