Примери за използване на Potassium channel на Английски и техните преводи на Български
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Fampyra is a potassium channel blocker.
The active substance in Fampyra, fampridine,is a potassium channel blocker.
Cloned human cardiac potassium channel(hERG) trafficking in vitro was inhibited by 75% at 30μM of saquinavir.
Trobalt acts by keeping the potassium channels open.
Flupirtine is a‘selective neuronal potassium channel opener'(SNEPCO) that acts by reducing the excessive electrical activity that leads to many pain states.
Flupirtine works as a‘selective neuronal potassium channel opener'.
In addition, the activation of the potassium channel leads to cardioprotective effects mimicking ischemic pre-conditioning.
This belongs to a group of medicines called‘potassium channel activators'.
In addition, the activation of the potassium channel leads to cardioprotective effects mimicking ischemic pre-conditioning.
This means that it opens specific pores on nerve cells called potassium channels.
Nicorandil is a hybrid of potassium channel opener and nitrate.
Fampyra contains the active substance fampridine which belongs to a group of medicines called potassium channel blockers.
Nicorandil is a hybrid of potassium channel opener and nitrate.
A potassium channel opening action provides arterial vasodilation, thus reducing afterload, while the nitrate component promotes venous relaxation and a reduction in preload.
This process requires energy-driven potassium channels to move charge against a gradient.
The chemical element of pinacidil belongs to the group of potassium channel activators.
Amifampridine blocks voltage-dependent potassium channels, thereby prolonging pre-synaptic cell membrane depolarisation.
In vitro data show that the IC50 for the inhibitory effect of ceritinib on the hERG potassium channel was 0.4 micromolar.
Repaglinide closes ATP-dependent potassium channels in the β-cell membrane via a target protein different from other secretagogues.
Amglidia is effective in patients with specific genetic mutations(beta-cell ATP-sensitive potassium channel and chromosome 6q24).
Molecular Dynamics Simulation of a potassium channel in interaction with TRX2 potassium channel opening property-© Oxford Biolabs Ltd.
He is author of multiple peer-reviewed publications andinternational patents in the field of potassium channel research and Androgenetic Alopecia.
However, as a known potent potassium channel opener, it can be assumed that the drug targets the same protein structures(potassium channels) as TRX2® does.
The most important and surprising finding of the study was that a single mutation in a potassium channel encoding gene KCNC1 explains a significant proportion of unsolved PME cases.
Flupirtine is a‘selective neuronal potassium channel opener' that acts by opening Kv7 potassium channels leading to functional N-methyl-D-aspartate receptor antagonism.
In contrast to the group of sodium channels, in which one drug can be replaced by another within the same class,it is unacceptable to do this with potassium channel blockers because of the difference in their mechanism.
The active substance in Firdapse, amifampridine,is a potassium channel blocker, which prevents charged potassium particles from leaving the nerve cells.
Neonatal diabetes, including diagnosis in infants younger than age 6 months, is most likely due to an inherited defect of the iKir6.2subunit potassium channel of the islet beta cells, and genetic screening is indicated.
Granisetron has been shown to block both sodium and potassium channels, which potentially affects both depolarization and repolarization through prolongation of PR, QRS, and QT intervals.
The new mutation identified in the study disrupts the function of a potassium channel, KV3.1, which has a central role in signal transmission in the brain.