英語 での Retroviruses の使用例とその 日本語 への翻訳
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Scientists know that retroviruses can permanently alter DNA.
Retroviruses can be used as vectors to deliver new genes to animal cells.
Scientists are working on ways to use retroviruses as vectors in gene therapies.
The study was published in the journal,AIDS Research and Human Retroviruses.
They're called retroviruses, and they actually change their host cell's DNA.
Many gene therapy clinical trials rely on retroviruses to deliver the desired gene.
Although HIV and the newly identified virus group are different,they are both retroviruses.
If done correctly, retroviruses can be engineered to carry genes into the body.
And some researchers are looking into how to use retroviruses themselves as treatments.
Our discovery of reverse transcriptase helped to clarify the life cycle of RSV andother retroviruses.
The retroviruses are typically replication-deficient(i.e. they are incapable of generating infectious particles).
But researchers are looking into ways to make retroviruses insert new genes only in very specific spots.
Endogenous retroviruses(ERVs) are remnants of ancient retroviral infections, and comprise nearly 8% of the human genome.
The research helped establish that the humanDNA contains much more residues of retroviruses than it was expected.
Retroviruses are a special group of viruses including some which are dangerous, such as HIV, while others are believed to be harmless.
But the estimate is 5-8% of the human genome is from viruses,is from ancient retroviruses that incorporated themselves into the human germ line.
The genes that control the production of various proteins in the bodyrepresent a smaller proportion of our DNA than endogenous retroviruses.
David Baltimore showed that retroviruses have a gene for reverse transcriptase(RT) called pol, and also carry the RT enzyme itself into cells.
A research group at Lund University inSweden has now discovered a mechanism through which these retroviruses may have an impact on gene expression.
At the recent Conference on Retroviruses and Opportunistic Infections(CROI) in Seattle, I had the pleasure of meeting with several doctors and clinicians for a very fruitful talk.
So instead of programming computers,we're using things to program viruses or retroviruses or proteins or DNA or RNA or plants or animals, or a whole series of creatures.
Scientists do not expect similar results- the number of retroviruses was quite large, Coffin's group found only 20 endogenous retroviruses, one of them was completely preserved as the virus and the rest were only fragments in the DNA.
The viruses studied by Johan Jakobsson andhis colleagues in Lund are called endogenous retroviruses(ERV) as they have existed in the human genome for millions of years.
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SiNA expressing viral vectors can be constructed based on, but not limited to,adeno-associated virus, retrovirus, adenovirus, or alphavirus.
It is called the porcine endogenous retrovirus(PERV), and this virus has the potential to cause a viral epidemic similar to HIV.