Phenoxybenzylamine inhibits the function of the NS3 protein by stabilizing an inactive conformation with an IC50 of about 500 μM against FL NS3/4a.
生物转化在肝脏(主要是通过与葡糖醛酸和硫酸共轭)到无活性的代谢产物。
Biotransformed in the liver(mainly by conjugation with glucuronic acid andsulfuric acid) to inactive metabolites.
在一些情况下,活性药物通过由无活性(或活性较低)代谢。
In some cases, an active drug is made inactive(or less active) through metabolism.
但其最重要的特征是它可以针对在受感染的人体细胞中“隐藏”无活性的HIV病毒颗粒库。
But its most important feature is that it can target thereservoir of HIV virus particles that“hide” inactive within infected human cells.
在完成他们的行动后,儿茶酚胺代谢为无活性的化合物。
After completing their actions, catecholamines are metabolized to inactive compounds.
它通常存在于生长中的胎儿中,但在成人组织中无活性。
It is usually present in the growing fetus but inactive in adult tissue.
这是关键信息,因为当装配出错时,无活性酶会导致N2O释放。
This is keyinformation because when assembly goes wrong, inactive enzyme leads to release of N2O into the atmosphere.”.
免疫系统正常的人在初次感染之后很少发生CMV症状,病毒通常保持无活性或潜伏在体内一生。
People with normal immune systems rarely develop CMV symptoms after initial infection,with the virus typically remaining inactive or latent in the body for life.
在完成他们的行动之后,儿茶酚胺代谢为无活性的化合物。
After completing their actions, catecholamines are metabolized to inactive compounds.
通常,它们的前体(无活性形式:胰蛋白酶原和糜蛋白酶原)在胰腺中生成并在小肠内运输。
Normally, their precursors(their inactive forms: trypsinogen and chymotrypsinogen) are produced in the pancreas and transported to the small intestine.
它通常存在于生长中的胎儿中,但在成人组织中无活性。
It is usually present in the growing foetus but is inactive in adult tissue.
现在,科学家们也知道为什么会这样:突变的Gq蛋白似乎偶尔也会恢复为无活性形式。
Scientists now also know why this is so:The mutated Gq proteins also seem to occasionally revert into their inactive form.
该物质“附着”在蛋白质上,并确保它们保持无活性形式。
The substance“clings” to the proteins and ensures that they remain in their inactive form.
也就是说,当它到达肌肉组织时,一种特定的酶与它结合,并使其变得无活性,从而失去一些合成代谢作用。
Namely, when it reaches the muscular tissues, a particular enzyme binds to it,and makes it become inactive, thus losing some of its anabolic effects.
其他的代谢产物均无活性。
All other metals remain inactive.
个基因无活性事件中的3个有胚胎缺陷。
Three of 19 gene inactivation events had embryonic defects.
这种激素相对无活性,但可以在肝和其他组织中转变成活性更高的T3。
This hormone is relatively inactive, but it is converted into the much more active T3 in the liver and other tissues.
其中三个是催化无活性的,并且它们结合成ADP。
Three of them are catalytically inactive and they bind ADP.
多柔比星的消除很大程度是药物代谢转化为一系列无活性或活性较低的产物。
The clearance of doxorubicin occurs to a substantialextent by metabolic conversion to a number of less active or inactive products.
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