The newly melanopsin-expressing ganglion cells provided an enhancement of visual function in rd/rd mice: the pupillary light reflex(PLR)returned almost to normal;
Restricting pacifier use to just before a child fell asleep, though,returned the risk to almost normal, a follow-up study in 2000(also in Pediatrics) found.
The two groups' different mutations completely eliminated specific cell types- presumably those directly affected by the disrupted gene-but most other cells differentiated almost normally.
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