Cap structure” or“terminal cap moiety” means chemical modifications, which have been incorporated at either terminus of an antisense compound.
在某些情况下,基因序列起作用,但在其他情况下,对DNA的化学修饰可能很重要。
In some cases gene sequences play a role,but in other cases, chemical modifications to DNA may be important.
一种技巧就是将当胚胎细胞转化为特化细胞时DNA发生的化学修饰进行移除。
One trick was to undo chemical modifications in the DNA that occur when embryonic cells turn into specialized cells.
最后,肽侧链也可以共价修饰,例如,磷酸化除了切割,磷酸化可能是蛋白质最重要的化学修饰。
Finally, the peptide side chains can also be modified covalently, e.g., phosphorylation Aside from cleavage,phosphorylation is perhaps the most important chemical modification of proteins.
在2015年的一项研究中,Cohen和同事们发现了一个可能因素:一种被称为乙酰化作用的化学修饰。
In a 2015 study,Cohen and colleagues found one possible factor: a chemical modification known as acetylation.
四年半后,研究人员抽取了小孩子们的DNA样本,以分析一种叫做DNA甲基化的化学修饰。
Four-and-a-half years later,DNA swabs were taken of the kids to analyse a biochemical modification called DNA methylation.
四年半后,研究人员抽取了小孩子们的DNA样本,以分析一种叫做DNA甲基化的化学修饰。
Then at 4½ years old, the researchers sampled thechildrens' DNA to track a biochemical modification known as DNA methylation.
单个tRNA的化学修饰是蛋白质合成期间解码过程的关键步骤。
Chemical modification of individual tRNAs is a critical step for the decoding process during protein synthesis.
在人体内,细胞通过改变DNA和相关蛋白质的化学修饰来打开和关闭基因。
In the human body,cells turn genes on and off by means of chemical modifications that change DNA and related proteins.
除了切割,磷酸化可能是蛋白质最重要的化学修饰。
Aside from cleavage,phosphorylation is perhaps the most important chemical modification of proteins.
不仅不同的mRNA翻译成不同的蛋白质,而且很多蛋白质被翻译后也在细胞中会有非常多样的化学修饰。
Not only does the translation from mRNA cause differences,but many proteins also are subjected to a wide variety of chemical modifications after translation.
Chemical modifications such as DNA methylation control mammalian genes, serving as bookmarks for when a gene should be used- a phenomenon known as epigenetics.
根据特定的化学修饰,基因可以开启或关闭。
Depending on the specific chemical modifications, genes can be turned on or off.
我们认为我们的化学修饰可以保护DNA末端。
We think our chemical addition protects the ends.
她认为,姜黄素的化学修饰形式可能会在到达组织方面更有效。
She thinks that chemically modified forms of curcumin might prove more effective at reaching tissues.
人们已经知道的化学修饰抗体“Fc区改变它们之间的相互作用与免疫细胞,包括B细胞,产生抗体。
It was already known that chemical modifications to antibodies' Fc region altered their interactions with immune cells, including B cells, which produce antibodies.
In 2013, Steve Horvath(UCLA)described the remarkable mathematical precision by which chemical modifications on DNA called methylation, changes with age.
在综述参见Ravetch实验室工作表明一个新的替代:化学修饰抗体的Fc区。
Work in the Ravetch lab suggests a new alternative: chemical modifications to the Fc region of antibodies.
生物年龄是通过测量DNA甲基化来确定的,甲基化是DNA的一种化学修饰,是正常老化过程的一部分。
Biologic age was determined by measuring DNA methylation, a chemical modification to DNA that is part of the normal ageing process.
DNA甲基化是影响基因表达在不同细胞背景下的DNA化学修饰。
DNA methylation is a chemical modification of DNA that affects gene expression under different cellular contexts.
他们使用化学修饰的“指导RNA”(gRNA)来提高整体编辑效率。
They used chemically modified"guide RNAs"(gRNAs) to enhance the overall editing efficiency.
这些组蛋白的各种化学修饰将导致相关基因活性的增加或减少。
Various chemical modifications of these histone proteins will result in an increase or decrease in the relevant gene activity.
对组蛋白的化学修饰-已知响应于细胞信号或环境条件而发生-可以影响基础DNA的表达。
Chemical modifications to histones- which are known to occur in response to cell signals or environmental conditions- can affect the expression of the underlying DNA.
中文
Bahasa indonesia
日本語
عربى
Български
বাংলা
Český
Dansk
Deutsch
Ελληνικά
Español
Suomi
Français
עִברִית
हिंदी
Hrvatski
Magyar
Italiano
Қазақ
한국어
മലയാളം
मराठी
Bahasa malay
Nederlands
Norsk
Polski
Português
Română
Русский
Slovenský
Slovenski
Српски
Svenska
தமிழ்
తెలుగు
ไทย
Tagalog
Turkce
Українська
اردو
Tiếng việt