If cell activation, even off ART, could be prevented, then this would provide long-term remission from HIV infection- a so-called functional cure.
他们找到了6个信号通路能阻止细胞死亡,衰老细胞激活它们,便存活下来。
They identified six signalling pathways that prevent cell death,which senescent cells activate to survive.
第一代CAR介导的T细胞激活是通过CD3z链或FceRIg上的酪氨酸激活基序完成的。
The first generation of CAR-mediated T cell activation is accomplished by a tyrosine activation motif on the CD3z chain or FceRIg.
由于最近确定了肥大细胞激活综合征,因此对该病症或其原因知之甚少。
Because mast cell activation syndrome was identified recently, there's scant knowledge about the condition or its causes.
SciRep:科学家鉴别出参与T细胞激活的新分子有望帮助开发新型癌症免疫疗法.
Sci Rep:Scientists identify new molecules involved in T cell activation, which is expected to help develop new cancer immunotherapy.
由于Treg抑制和效应物细胞激活的结合效应,GITR是癌症免疫治疗干预的唯一机会(16)。
Due to the combined effects on both Treg suppression and effector cell activation, GITR represents a unique opportunity for immunotherapeutic intervention in cancer(16).
这种反应适用于患有肥大细胞激活综合征的人:组胺释放可导致一切肿胀。
This response backfires in people who have mast cell activation syndrome: the release of a histamine can cause everything to swell.
Besides MS, Frequency says its progenitor cell activation technology has potential applications in diseases affecting muscles, the gastrointestinal tract, skin, and bones.
Green和同事们在以往的研究中证实,c-Myc还驱动了T细胞激活后的代谢改变。
Previous research from Green and his colleagues showed that c-Myc alsodrives metabolic changes following T cell activation.
同时,研究还证实,这种抗肿瘤免疫力主要是通过NK细胞激活NKG2D和CD16Fc受体介导的。
At the same time, research also confirms that this anti-tumorimmunity is mainly mediated by NK cell activation of NKG2D and CD16 Fc receptors.
在这项研究中,研究人员采用专门饲养的小鼠确定了mTORC1在T细胞激活和增殖中所起的作用。
In this study, researchers used specially bredmice to identify mTORC1's role in T cell activation and proliferation.
组胺和/或胰蛋白酶血液测试可以用来帮助诊断过敏性反应或肥大细胞激活。
Histamine and/or tryptase blood tests may be used to help diagnose anaphylaxis ormast cell activation.
相反,研究人员发现CD40对穆勒细胞激活这些细胞类型,这往往卷入了炎症.
Instead, the researchers discovered CD40 on Mueller cells activates these cell types, which are often implicated in inflammation.
当其DNA被破坏,细胞激活基因以修复病变并减缓许多其他病毒的转录。
When its DNA is damaged, a cell activates genes to repair the lesion and slows down the transcription of many others.
此外,B细胞激活因子(BAFF)在SSc患者中以升高的水平存在并且与疾病严重性相关。
In addition, B cell activating factor(BAFF) is present at elevated levels in patients with SSc and correlates with disease severity.
作为一项测试,他们刺激人类细胞激活Wnt信号通路,该通路在胚胎发育和癌症发生中发挥作用。
As a test, they stimulated human cells to activate the Wnt signaling pathway, which plays a role in the development of embryos and in cancer.
我们的目的是进一步阐明dectin-2在细胞激活,宿主防御和免疫中的作用。
We aim to further elucidate the role of dectin-2 in cellular activation, host defence and immunity.
CD22 cross-links with BCR, inhibits B cells' response to autoantigens,and prevents autoreactive B cell activation, thereby inhibiting the development of autoimmune diseases.
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