What is the translation of " 错误折叠 " in English?

• misfolded
• misfolding
• incorrectly folded

Examples of using 错误折叠 in Chinese and their translations into English

错误折叠经常与诸如阿尔茨海默氏症和帕金森病的疾病有关。
Misfolding is frequently associated with diseases such as Alzheimer's and Parkinson's.

Loyola的研究重点是这些错误折叠的蛋白质团块如何侵入健康的脑细胞。
The Loyola study focused on how these misfolded protein clumps invade a healthy brain cell.

研究组在该篇论文中也提出了这些错误折叠的蛋白也许能作为植物记忆的一种基本形式。
In its paper, the team proposed that these misfolded proteins may serve as the basis for a form of memory in plants.

受损线粒体功能和蛋白质错误折叠的相同因素被认为在阿尔茨海默病、帕金森病和ALS中越来越重要。
The same factors of impaired mitochondrial function and protein misfolding are recognized as increasingly important in diseases like Alzheimer's disease, Parkinson's disease, and ALS.

该系统确保错误折叠的蛋白质通过泛素介导的蛋白质降解系统被破坏，而不是被运输到细胞质膜上。
This system ensures that the incorrectly folded protein is destroyed through ubiquitin-mediated protein breakdown instead of being transported out to the cell wall.

UPR的主要任务是检测错误折叠蛋白，即不符合正确形状要求的蛋白。
A central task of UPR is to detect misfolded proteins, i.e. proteins that do not have the correct shape to do their job.

由于蛋白质错误折叠可以是灾难性的细胞，蛋白质被称为热休克蛋白（HSP）已经发展到促进适当的蛋白质折叠。
Since protein misfolding can be disastrous for cells, proteins known as heat shock proteins(HSPs) have evolved to facilitate proper protein folding.

该系统确保错误折叠的蛋白质通过泛素介导的蛋白质降解系统被破坏，而不是被运输到细胞质膜上。
The incorrectly folded protein is destroyed through ubiquitin-mediated protein breakdown instead of being transported out to the cell wall.

Lu的早期研究发现，改变产生错误折叠tau的小鼠也产生较低水平的NMNAT2。
Lu's earlier research found that mice altered to produce misfolded tau, also produced lower levels of NMNAT2.

其蛋白质错误折叠循环扩增(PMCA)技术的工作原理是放大现有的错误折叠的蛋白质，然后打破他们成更小的碎片。
Their protein misfolding cyclic amplification(PMCA) technology works by amplifying existing misfolded proteins and then breaking them up into smaller pieces.

朊病毒引发错误折叠和他们正确折叠的蛋白质对应物的聚集，但它们通常需要某种“种子”才能开始。
Prions trigger the misfolding and aggregation of their properly folded protein counterparts, but they usually need some kind of"seed" to get started.

细胞可能降低破坏细胞核中错误折叠蛋白的标准，避免它们干扰重要的遗传信息。
Cells might lower the bar for destroying misfolded proteins in the nucleus, to avoid them interfering with important genetic information.

现在科学家已经证明，提高细胞处理错误折叠的蛋白质可以让他们从细胞内聚集能力。
Now scientists have shown that boosting the cells' ability to process misfolded proteins could keep them from aggregating inside the cell.

该研究比较了两种高灵敏度的朊病毒检测方法：RT-QuIC（实时震动诱导转化）和sPMCA（连续蛋白质错误折叠循环扩增）。
During the study two detection methods were compared: RT-QuIC(real-time quaking-induced conversion) and sPMCA(serial protein misfolding cyclic amplification).

研究人员成功地通过简单的血液检查诊断出这种错误折叠；.
In the new study, a research team headed by Gerwert successfully diagnosed this misfolding with a simple blood test;

在那里，错误折叠的IAPP也触发了大型IAPP聚合的形成。
There, too, misfolded IAPP triggered the formation of large IAPP aggregates.

人们越来越多地认识到神经退行性疾病具有常见的细胞和分子机制，包括蛋白质错误折叠和聚集。
Neurodegenerative diseases are increasingly being realized to have common cellular and molecular mechanisms including protein misfolding and aggregation.

研究表明，错误折叠的蛋白质可能是身体许多疾病过程的心脏。
Research suggests that misfolded proteins may be at the heart of numerous disease processes in the body.

错误折叠和聚集的蛋白质”不仅与阿尔茨海默氏症有关，还与帕金森病和许多其他人类疾病有关。
Misfolded and aggregated proteins" are linked not only with Alzheimer's, but also with Parkinson's and many other human diseases.

公司设计、发现并开发了一系列治疗和诊断产品用于预防以及修复由蛋白错误折叠导致的疾病。
The Company designs, discovers and develops therapeutic and diagnostic products to prevent and modify diseases caused by misfolding proteins.

细胞膜中错误折叠的蛋白质和之后细胞电学特征的变化是导致细胞退化的原因。
Misfolded proteins in the cell membrane, and subsequent changes in the electrical properties of cells, provide the explanation for the cell degeneration.

分子伴侣的功能之一是帮助MHC-1蛋白折叠成它们的活性形状并稳定它们，以防止错误折叠和聚集。
One of the functions of chaperones is to help MHC-1 proteins fold into their active shapes and stabilize them to prevent misfolding and aggregation.

已知暴露于低pH会使抗体不稳定，导致聚集和错误折叠.
Exposure to low pH is known to destabilize the antibody, causing aggregation and misfolding.

问题变成了，在其他条件下起作用的相同生物学机制是否是由错误折叠蛋白的堆积引起的？”.
And the question became, is the same biology at work in other conditions caused by a buildup of misfolded proteins?".

目前的观点是许多神经退行性疾病是由错误折叠的蛋白质引发的。
The current view is that many neurodegenerative diseases are triggered by misfolded proteins.

根据武田，AL型淀粉样变性是一种罕见、侵略性蛋白质错误折叠疾病。
AL amyloidosis is a rare and aggressive protein misfolding disorder.

我们并不知道像TMED9这样的货物受体能够阻断并最终干扰错误折叠蛋白的破坏。
We did not know that a cargo receptor like TMED9 could block and ultimately interfere with the destruction of a misfolded protein.

该研究比较了两种高灵敏度的朊病毒检测方法：RT-QuIC（实时震动诱导转化）和sPMCA（连续蛋白质错误折叠循环扩增）。
The study compared two highly-sensitive prion detection methods: RT-QuIC(real-time quaking-induced conversion) and sPMCA(serial protein misfolding cyclic amplification).

但是科学家们一直在努力难以确切地理解tau是如何从其正常的功能形式转变为错误折叠的有害形式的。
But scientists have struggled to understand exactly how tau converts from its normal, functional form into a misfolded, harmful one.

多年前，科学家发现诸如疯牛病和Creutzfeldt-Jakob病等神经系统疾病是由错误折叠的蛋白(called病毒)引起的。
More than 30 years ago, scientists discovered that neurological illnesses such as mad cow and Creutzfeldt-Jakob diseases are caused by misfolded proteins called prions.