The data includes isozyme loci and a table linked with parental Southern images of each probe and Nucleotide sequence, and other related clone information.
At the patients accepting at the same time preparations inhibitors of an isoenzyme 3?4 of P450 cytochrome(erythromycin) the initial dose Sildenafil makes 50 mg.
In vitro studies have shown that the isozyme CYP2C9 plays an important role in this metabolic transformation, the CYP3A4 isoenzyme plays an additional role.
Precautions should be prescribed in high doses Cipralex simultaneously with cimetidine in high doses,which is a potent inhibitor of the isoenzyme CYP2D6, CYP3A4 and CYP1A2.
In vitro studies have shown that the isoenzyme CYP2C9 plays an important role in this metabolic transformation, the isoenzyme CYP3A4 has an additional significance.
Plasma concentrations of tolbutamide, phenytoin and warfarin in long-term appointment of sertraline at a dose of 200 mg/ day does not change, therefore,it can be concluded that sertraline does not inhibit isoenzyme CYP2C9.
According to the pharmacological activity of a 4-equivalent Atomoxetine gidroksiatomoksetin, but it circulates in plasma at much lower concentrations. Although 4-gidroksiatomoksetin initially formed with the participation of CYP2D6, in people with insufficient activity CYP2D6 gidroksiatomoksetin4 can be formed by some other isozymes of cytochrome P450, but more slowly.
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