The number of guitars they own, the numbers of effectors they play with like they were toys, the different amps, the combination they make between all of these….
By drawing on their expertise in drug discovery, Ding's team identified a small-moleculedrug that can successfully reprogram effector T cells into regulatory T cells.
Several subsets of effector CD4+ T cells arise, depending on the type of infection, which have distinct transcriptional programs driving their differentiation.
Integrating these advances has led to the recognition that the balance between regulatory and effector T cells determines disease risk, timing of disease activation, and disease tempo.
The effector functions of antibodies are determined by sequences in the Fc region, the region which is also recognized by Fc receptors(FcR) found on certain types of cells.
All the targets are used at 5000 cells per well in microtitration plate and the Effector on target ratio is indicated in the figures(usually 4 effectors per target cells).
The effector functions of antibodies are determined by sequences in the Fc region, which region is also the part recognized by Fc receptors(FcR) found on certain types of cells.
However, it is unclear how this is regulated andwhether memory cells are formed from the effector cells or differentiate separately(see the Perspective by Feau and Schoenberger).
An Fc fusion combines the Fc region of an antibody,and thus its favorable effector functions and pharmacokinetics, with the target-binding region of a receptor, ligand, or some other protein or protein domain.
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