Higher than grade 3 toxicity andtreatment discontinuations that resulted from drug-related toxic effects were higher in the pemetrexed group than in the placebo group.
Toxicology: This program discusses the scientific principles underlying the toxic actions of various substances and introduces the numerous challenges of toxicology.
This program discusses the scientific principles underlying the toxic actions of various substances and introduces the numerous challenges of toxicology.
発育中の胎児,乳児及び幼児は特に脳における水銀の毒性作用を受けやすい。
The developing fetus, infants,and young children are especially vulnerable to the toxic effects of mercury on the brain.
This course will establish the scientific principles underlying the toxic actions of various substances and will introduce the various challenges within the field of toxicology.
動物の体を分解し中毒にする駆虫薬と死んだ虫の両方が、毒性作用を引き起こす可能性があります。
Both antihelminthic drugs and dead worms, which decompose and poison the body of an animal,can cause a toxic effect.
腎不全の患者に高用量の薬物を使用する場合、中枢神経系に対する毒性作用が可能である。
When using the drug inhigh doses in patients with renal insufficiency, a toxic effect on the central nervous system is possible.
There were no significant differences in toxic effects, hospitalization, or treatment-related death by age group, although elderly patients received less treatment.
ATOまたはATRAのどちらかが毒性作用の結果として中止された場合には、GOが代わりに用いられた。
GO was substituted if either ATO orATRA were discontinued as a result of toxicity.
網膜上のivabradinaの毒性作用に関するデータは現在ありません。,税込。
There is currently no data on the toxic effect of ivabradine on the retina, incl. prolonged use.
これから期待される主な症状は、消化管および肝臓への毒性作用、ならびに骨髄抑制である。
The main symptoms that are expected from this are toxic effects on the digestive tract and liver, as well as bone marrow suppression.
Radiation therapy and alkylating agents are used as last resorts for patients with NF1,given the theoretically heightened risk of inducing neurologic toxic effects and second malignancy in this population.
According to preclinical testing,it was found that the drug has a toxic effect on the fetus of the rat, although, at the same time, it does not affect fetal development in monkeys with rabbits.
The most frequent toxic effects(stomatitis and hand-foot syndrome) were usually observed after the first cycle, and were more pronounced after dose rates exceeded 10 mg/m2 per week.
As a result of the conducted studies, it wasit has beenestablished that this agent does not have a toxic effect on plants, that is, the consumption of fruits processed with this fungicide is absolutely harmless.
This, coupled with emerging knowledge about the toxic effects such particles have on biological organisms, including mammals, has led to concern and actions to monitor and reduce microplastics emissions.
Some researchers have raised concerns over the toxic effects of these medications, suggesting that patients may only benefit from the medication in the short-term.
Diarrhea, appearing in more than 24 hours after treatment(delayed diarrhea),It is a consequence of cytostatic effect and dose-limiting toxic effect of irinotecan.
The chelators are designed to compete with the heavy metals include reactive groups physiological preventing orreversing the toxic effects and increase their excretion.
This study identified second malignancies(cumulative incidence, 1.7%)and cardiac toxic effects(cumulative incidence, 4.7%) as significant long-term risks.
Febrile neutropenia is most often observed in patients who repeatedly underwent massive cytotoxic and radiation therapy used in malignant tumors andis regarded as a hyperergic reaction in response to the toxic effects of medications.
Ingredient allicin protect colon cells from the toxic effects of cancer-causing chemicals, even if they still have the ability to stop the growth of cancer cells began to grow.
In other words, patients assigned to pazopanib first had a true 2-week break from treatment,and their drug preference was assessed at the peak period of toxic effects from sunitinib;
Removing neutrophils, the only CXCR2-expressing blood cells,from the circulation of normal mice rendered them resistant to the toxic effects of cuprizone.
Violation of the liver and kidneys(Cl creatinine less than 60 ml/ min),tk. cumulative effect is possible and the development of toxic effects, peripheral neuropathy.
A retrospective study that compared 145 patients who received imatinib before transplant with a historical cohort of 231patients showed no difference in early hepatic toxic effects or engraftment delay.[28].
人の患者は投与を受け325分の点滴中のMg;毒性作用の臨床的または実験症状は認められません。
Two patients received a dose of 32 mg in the form of 5-minute infusion;no clinical or laboratory manifestations of toxic action not observed. Symptoms: clinically significant hypocalcemia, gipofosfatemiя.
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