The detection of the enzyme interacting with the substrate ensures utmost specificity andenables evaluation of the localized activity of a particular enzymatic species.
Sometimes our scientists found that an individual enzyme might notwork so well with other enzymes, or that a particular enzyme just cannot be kept active in solution.
This is called energy(ATP) dependent proteolysis,in which ubiquitin is conjugated to targeted proteins by specific enzymes in a process called"ubiquitination.
Most staphylococci produce a specific enzyme beta-lactamase(penicillinase) and are resistant to benzylpenicillin(penicillinase-forming 80-90% strains of Staphylococcus aureus).
This means that if a certain enzyme is deficient, its basic substrate is simply not digested in the lysosome, which is why it accumulates and causes unfavorable consequences.
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