Примеры использования Proliferation and differentiation на Английском языке и их переводы на Русский язык
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EpCAM is also involved in cell signaling,migration, proliferation, and differentiation.
IL-20 regulates proliferation and differentiation of keratinocytes during inflammation, particularly inflammation associated with the skin.
In animals, MADS-box genes are involved in muscle development and cell proliferation and differentiation.
Orexins, anorexins, adipocyte proliferation and differentiation regulators, decouplers of oxidative phosphorylation, etc.
Growth factors- natural human proteins that can stimulate the growth, proliferation and differentiation of cells.
Exogenous recombinant IL-6 influences the proliferation and differentiation of cultured myoblasts derived from human or murine muscle via the activation of the STAT3 signaling pathway 35.
According to modern views, canonical branch of Wnt signaling pathway is involved in cell proliferation and differentiation.
It is still unknown whether Epo/EpoR directly cause"proliferation and differentiation" of erythroid progenitors in vivo, although such direct effects have been described based on in vitro work.
Very good results have been shown in the treatment of androgenic alopecia,where PRP stimulates the proliferation and differentiation of the stem cells in the hair follicle.
This hormone stimulates proliferation and differentiation of red cell precursors, which activates increased erythropoiesis in the hemopoietic tissues, ultimately producing red blood cells erythrocytes.
It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation.
In vivo bioimaging is traditionally employed to study migration direction, proliferation and differentiation of stem cells in experiment and in clinical environment.
The role of stromal microenvironment in hematopoietic stem cell transplantation(HSCT)is based on their nonlineage-specific effects upon proliferation and differentiation of HSCs.
The maternal-fetal interface(the placenta)plays a crucial role in growth, proliferation and differentiation of cells and its size is influenced by changes in the nutritional environment at different stages of gestation 22,62.
Many metabolic processes occur with the participation of iron: synthesis of steroids, metabolism of drugs,DNA synthesis, proliferation and differentiation of cells, regulation of genes.
Together, these data suggest that myostatin has direct effects on the proliferation and differentiation of osteoprogenitor cells,and that myostatin antagonists and inhibitors are likely to enhance both muscle mass and bone strength.
Slow silk fibroin biodegradation can be an advantage when used in tissue engineering in cases when a long period of time is required for cell proliferation and differentiation in an implant 6.
Numerous studies, both in vivo and in vitro, have shown that neurotrophins have proliferation and differentiation effects on CNS neuro-epithelial precursors, neural crest cells, or precursors of the enteric nervous system.
Mechanical properties of extracellular matrix such as tensile strength and elasticity are significant biophysical parameters,since they can influence cell morphology, their proliferation and differentiation 13.
Endothelial progenitor cells express FGF receptors and it has been demonstrated that FGF regulates the proliferation and differentiation of endothelial progenitor cell-like MSCs through the ERK1/2 signaling pathway 57.
Voltage-gated chloride channels display a variety of important physiological and cellular roles that include regulation of pH, volume homeostasis, organic solute transport, cell migration,cell proliferation and differentiation.
An important component of barriergenesis is angiogenesis,which in many ways depends on activity, proliferation and differentiation of endothelial progenitor cells, in particular, microcirculation vessels in the brain are formed of meningeal vessels and spread to parenchyma of developing brain by angiogenic mechanism 13.
At all the barriergenesis stages, development of local microenvironment supported by regulatory molecules is of great importance, ensuring various intercellular interactions,controlling cell proliferation and differentiation 34.
These characteristics are the following:the presence of adhesive surface promoting cell proliferation and differentiation; biocompatibilityand no immunologic rejection; non-toxicity; biodegradation, its rate should correspond to self-tissue growth; optimal pore size for spatial cell distribution, vascularization, as well as the diffusion of nutrients and removal of wastes 7.
The studies of stem cell differentiation on a chip which have become a trend since the middle 2000-s[1],led to a conclusion on the necessity of multiparametric studies of the cell response in such systems resulting into changes of the cell proliferation and differentiation.
A representative of transforming growth factor beta family, neurotrophic factor GDNF, is secreted by glial cells(astrocytes, Schwann cells) and promotes preservation, proliferation and differentiation of various cell populations of the centraland peripheral nervous system 6, 7.
Further studies demonstrated that MSCs can be enriched with cell surface markers CD45neg CD31neg EpCAMneg Sca-1pos and play an important role as the epithelial progenitor cell niche to support their proliferation and differentiation in vitro24,33.
A solution like this makes a high adhesion of the stem(mesenchymal) cells to the matrix possible, providing high density of cells attachment to the given matrix, and also stimulation of proliferation and differentiation of the native tissue,and growth of new forming connective tissue fibers.
Nanoparticles from silk fibroin, encapsulating the antibacterial pharmaceutical gentamicin, after being applied on a titanium surface to achieve continuous release of the pharmaceuticals in vitro,increased the adhesion of osteoblasts, their proliferation and differentiation compared to the titanium surface with no such covering.
Clare Blackburn and colleagues show that established age-related thymic involution can be reversed by forced upregulation of just one transcription factor- FOXN1 in the thymic epithelial cells in order to promote rejuvenation, proliferation and differentiation of these cells into fully functional thymic epithelium.