Примеры использования Proteolysis на Английском языке и их переводы на Русский язык
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This is also called proteolysis.
In brain, they prevent unwanted proteolysis and are involved in several neurodegenerative diseases.
Then prosomatostatin changes into somatostatin by means of specific proteolysis.
Prognostic role of markers of proteolysis system in patients with ulcerative colitis.
Each catalytic β subunit also possesses a conserved lysine residue required for proteolysis.
Incubation parameters of the enzymatic agent SG-50 impact on the proteolysis degree of ground meat is studied in the paper.
However, high levels of oxidative damage increases the degree of cross-linking between protein fragments,rendering the aggregates resistant to proteolysis.
It further improves protein digestion by increasing the rate proteolysis of large protein molecules Theobald and Lückstädt, 2011.
It is not surprising, that the probable target, which possesses the activity similar to α-sectetase, is matrix metalloprotease-9(MMP-9),participating in matrix remodeling and proteolysis of some peptide factors.
It has been also established, that proteolysis of APP mediated by α-secretase is not amyloidogenic and prevents A β formation 31.
Analysis of ubiquitin-dependent increase in monoamine oxidase sensitivity to proteolysis and specific inhibition.
Getting mass spectra of the protein after proteolysis by trypsin in reflectron mode in the mass range 500-6500Da.
It is known that intracellular proteases called caspases degrade the cellular contents of the cell by proteolysis upon activation of the death pathway.
This article discusses the clinical and pathogenetic role of proteolysis system components in the colonic mucosa of patients with ulcerative colitis, and provides criteria for prediction of relapse and remission of the disease, allowing to complement modern diagnostic and treatment algorithm, and limit the use of steroid hormones.
In the article to obtain fractions of low molecular weight peptides by limited proteolysis of skim milk enzyme preparation"Pancreatin.
Note that only the step of substrate unfolding requires energy from ATP hydrolysis, while ATP-binding alone can support all the other steps required for protein degradation e.g., complex assembly, gate opening,translocation, and proteolysis.
The TGF-β activation process involves the release of theLLC from the matrix, followed by further proteolysis of the LAP to release TGF-β to its receptors.
There have been given evidences that the imbalance in cytokine system in acute inflammation provokes a cascade of metabolic disturbances related to the hyperproduction of active metabolites of oxygen,peroxynitrite, proteolysis products.
The poster title was"RNA-recognition motif RRM2 in TDP-43:oxidative stress leads to conformational change, proteolysis, formation of inclusion bodies, and neurodegenerative disease.
An important component of AD pathogenesis is neuroinflammation, the activity of which is mediated not only by microglia, showing cytotoxic potential in relation to the damaged neurons, but also by astroglial cells, participating in the regulation of a local inflammation, producing cytokines and forming multiprotein complexes- inflammasomes,providing intracellular proteolysis of proinflammatory cytokines.
Tangles are extracellular deposits of amyloid, consisting mainly of amyloid-beta(A β),formed by proteolysis of amyloid beta precursor protein(APP) by β- and γ-secretases 15, 16.
Exit from mitosis, starting at the metaphase to anaphase transition, occurs when the anaphasepromoting factor(APC/ C) is activated and tags a small number of target proteins, including cyclins and securin,with polyubiquitin chains that signal their proteolysis by the proteasome.
There are considered the most significant aspects of infusion therapy,the use of secretion inhibitors and proteolysis, the choice of antibiotics and antifungal agents, detoxication techniques, and nutrition regimens.
There is no clear evidence to date of harmful effects other than those caused by localised heating and ensuing chemical changes expression of heat shock proteins,denaturation, proteolysis, and inflammatory response.
The dimer of Hsp90, along with PTGES3(p23),has a multifunctional role in the protection of the receptor from proteolysis, constraining the receptor in a conformation receptive to ligand binding and preventing the premature binding of ARNT.
Additionally, an insert domain(ID, residues 638-756) resides within FnIII-2,containing the α/β furin cleavage site, from which proteolysis results in both IDα and IDβ domains.
The main pathophysiological mechanisms of EI is rapid accumulation of bacterial toxins, cellular debris, metabolites of oxidative stress, and other active substances in the body,as well as excessive proteolysis, against the background of developing inconsistency between excessive amount of toxic substances entering the tissues and the blood flow, and the capability of biological systems of body detoxification to transform, neutralize and eliminate these substances 2.
Reference: Buneeva O.A., Medvedeva M.V., Medvedev A.E.,Analysis of ubiquitin-dependent increase in monoamine oxidase sensitivity to proteolysis and specific inhibition, Biomeditsinskaya khimiya, 2008, vol: 54(6), 720-726.
With the exception of ANAPC2, each member of the cullin family is modified by Nedd8 andseveral cullins function in Ubiquitin-dependent proteolysis, a process in which the 26S proteasome recognises and subsequently degrades a target protein tagged with K48-linked poly-ubiquitin chains.