Приклади вживання Mrna Англійська мовою та їх переклад на Українською
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General kinetic analysis of the process of one mRNA species translation.
The mRNA transcribed from many genes is called polycistronic.
Inhibits LPS-induced NO production by suppressing iNOS mRNA expression.
These mRNA and proteins interact with each other with various degrees of specificity.
Multisubunit complex eEF1H in human glial tumors: from mRNA to protein.
The development and production cycle of the mRNA vaccine is shorter than that of traditional vaccines.
By lysing the cells, it is aimed at extracting and separating the organelles, proteins,DNA, mRNA or other biomolecules.
The potential mRNA target sites for the ribosomal protein L10 found in Streptomyces griseus and S.
Expression of cancer-associated genes in prostate tumors at mRNA and protein levels.
By injecting DNA or mRNA into the oocyte or developing embryo, scientists can study the protein products in a controlled system.
Ribosomes don't act directly on DNA, buton expendable“base pair copies” of DNA called messenger RNA, or mRNA.
The start and stop ends of the ORF are not equivalent to the ends of the mRNA, but they are usually contained within the mRNA.
In bacteria, translation occurs in the cell's cytoplasm,where the large and small subunits of the ribosome bind to the mRNA.
Key words: mRNA expression, DEK, BRCA1, COL6A1, ADGRE5, GNPDA1 genes, glutamine deprivation, IRE1 knockdown, U87 glioma cells.
In Bacteria, translation occurs in the cell's cytoplasm, where the large and small subunits of the ribosome are located,and bind to the mRNA.
In the end, the mRNA molecule separates from the DNA strand(which in turn has hydrogen bonds again) and the double helix is reestablished.
Methisazone(USAN) or metisazone(INN) is an antiviral drug that works by inhibiting mRNA and protein synthesis, especially in pox viruses.
Because prokaryotic mRNA does not need to be processed or transported, translation by the ribosome can begin immediately after the end of transcription.
The hormone-receptor complex then binds withDNA thus promoting DNA transcription and the mRNA formation which alters the synthesis of protein.
Aromatase mRNA levels in the oSDN were significantly greater in female-oriented rams than in ewes, whereas male-oriented rams exhibited intermediate levels of expression.".
The translation phase takes place in the cell cytoplasm andconsists of a process where the message present in the mRNA is decoded in the ribosome.
Additionally, Gentamicin includes misreading of the genetic code of the mRNA template, leading to incorporation of incorrect amino acids into the growing polypeptide chain.
Without mRNA, which is the template for protein synthesis, cell metabolism stops and lysis ensues.[4] The RNA polymerase of Amanita phalloides is insensitive to the effects of amatoxins; thus, the mushroom does not poison itself.[5].
For example, IL-17 has been shown to induce the expression of osteoclast differentiation factor(ODF) mRNA in osteoblasts Kotake et al., J. Clin.
The base pairing of tRNA and mRNA triplets is based on interlocking shapes and ordinary chemical attraction, but the proper pairing of tRNAs with amino acids requires much more than ordinary chemistry.
Like other amatoxins, ε-amanitin is an inhibitor of RNA polymerase II. Upon ingestion, it binds to the RNApolymerase II enzyme which completely prevents mRNA synthesis, effectively causing cytolysis of hepatocytes(liver cells) and kidney cells.[1].
Poly-A RNA was purified with the Dynabeads mRNA purification kit(Invitrogen) following the manufacturer's instructions and was treated for 30 min at 37°C with TURBO DNase(Ambion; 0.2 units/1 μg of RNA).
The fact that they are not simply have a complete set of genetic material(it has each asexual cell of the body), but unlike other somatic cells of the adult organism in which some genes are active andon which there is a synthesis of mRNA and the other are repressed, in them all genes retain potent activity.
The translation of mRNA can also be controlled by a number of mechanisms, mostly at the level of initiation. Recruitment of the small ribosomal subunit can indeed be modulated by mRNA secondary structure, antisense RNA binding, or protein binding.
In budding yeast(Sacharomyces cerevisiae), the homologue of METTL3, IME4 is induced in diploid cells in response to nitrogen and fermentable carbon source starvation andis required for mRNA methylation and the initiation of correct meiosis and sporulation.[1][2] mRNAs of IME1 and IME2, key early regulators of meiosis, are known to be targets for methylation, as are transcripts of IME4 itself.