Примери за използване на A cumulative dose на Английски и техните преводи на Български
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Lower than a cumulative dose of 12,00 fibre-days per cm3 over a  three-month period;
The approximately 180-day voyage from Earth to Mars would expose the spacecraft and its passengers to a cumulative dose of around 0.7 gray.
Lower than a cumulative dose of 6,00 fibre-days per cm3 over a  three-month period.
A cumulative dose of 72 mg/m² is still effective and associated with less cardiotoxicity than higher cumulative  doses.
Neutropenia usually occurs during the first or second week of induction therapy and following administration of a cumulative dose of≤ 200 mg/ kg.
It is recommended not to exceed a cumulative dose for the course of treatment of 4 mg/kg in patients with dapsone-induced methaemoglobinaemia.
Isotretinoin therapy should be initiated at a dose  of 0.5 mg/kg/d for 4 weeks andincreased as tolerated until a cumulative dose of 120-150 mg/kg is achieved.
In clinical studies,20% to 25% of the patients treated with a cumulative dose of cladribine 3.5 mg/kg over 2 years as monotherapy developed transient grade 3 or 4 lymphopenia.
Patients received either placebo(n= 437), or a cumulative dose of cladribine of 3.5 mg/kg(n= 433) or 5.25 mg/kg body weight(n= 456) over the 96-week(2-year) study period in 2 treatment courses.
Cardioxane is contraindicated in children and adolescents up aged 0 to 18 years of age who are planned to receive a cumulative dose of less than 300 mg/m2 of doxorubicin or the equivalent cumulative dose  of another anthracycline.
In this extension study,806 patients received either placebo or a cumulative dose of cladribine 3.5 mg/kg(in a  regimen similar to that used in CLARITY) over the 96-week study period.
Cardioxane is contraindicated in children aged 0 to 18 years who are planned to receive a cumulative dose of less than 300 mg/m2 of doxorubicin or the equivalent cumulative dose  of another anthracycline(see sections 4.4 and 4.8).
Compared with patients who received a  radiation dose  ofless than 5 mGy, those who received a cumulative dose of at least 30 mGy(mean dose,  51.13 mGy) had a  relative risk of leukemia of 3.18(95% CI 1.46- 6.94).
Renal tolerability of zoledronic acid was established in rats when given 0.6 mg/kg as 15-minute infusions at 3-day intervals,six times in total(for a cumulative dose that corresponded to AUC levels about 6 times the human therapeutic exposure) while five 15-minute infusions of 0.25 mg/kg administered at 2-3-week intervals(a cumulative dose that corresponded to 7 times the human therapeutic exposure) were well tolerated in dogs.
Subchronic and chronic toxicity In the intravenous infusion studies, renal tolerability of zoledronic acid was established in rats when given 0.6 mg/ kg as 15-minute infusions at 3-day intervals,six times in total(for a cumulative dose that corresponded to AUC levels about 6 times the human therapeutic exposure) while five 15-minute infusions of 0.25 mg/ kg administered at 2- 3-week intervals(a cumulative dose that corresponded to 7 times the human therapeutic exposure) were well tolerated in dogs.
B-cell lymphoma when receiving bevacizumab with a cumulative doxorubicin dose greater than 300 mg/m2.
It has been shown that no substantial additional benefit is to be expected beyond a cumulative treatment dose of 120-150 mg/kg.
In cats, no pharmacological effects on respiration andcardiovascular function were observed up to a cumulative intravenous dose of 10 mg/kg.
Patients received an  s.c. dose  of 0.125 mg/kg three times a  week or 0.054 mg/kg/day,both regimens giving a cumulative weekly dose of approximately 0.375 mg/kg.
This risk increases with cumulative dose.
Risk increases with increasing cumulative dose.
Hence, patients with multiple sclerosis should not receive a  lifetime cumulative dose greater than 72 mg/m².
The cumulative dose should not exceed 500 mSv.
The maximum lifetime cumulative dose should not exceed 72 mg/m2.
There was a  positive linear correlation between the cumulative dose of Lysodren and the plasma levels of mitotane.
Comparative clinical studies have shown that on average patients require a  lower cumulative dose and shorter treatment duration with GONAL-f compared with urinary FSH.
The researchers found that the higher a  patient's cumulative dose of anticholinergic medication over the 10 years before entering the study, the greater his or her risk of dementia.
For major surgery, a  median of 13 infusions(range 2 to 15 infusions)and a  median cumulative dose of 181 IU/kg(range 45 to 210 IU/kg) were required to maintain haemostasis.