Примери за използване на Combination with efavirenz на Английски и техните преводи на Български
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For combination with efavirenz+ PI, see below.
In some studies, Kaletra was used in combination with efavirenz or nevirapine.
For combination with efavirenz+ PI, see separate recommendations below.
Dose increases of indinavir/ritonavir when given in combination with efavirenz have not been studied.
In the first study in previously untreated patients,83% of the patients taking the Eviplera combination responded to treatment compared with 84% of the patients taking a combination with efavirenz.
Atazanavir and ritonavir to 400 mg and 200 mg, respectively, in combination with efavirenz could be considered with close clinical monitoring.
A higher incidence of rash was reported in patients treated with amprenavir in combination with efavirenz.
Nevirapine in combination with efavirenz exhibited a strong antagonistic anti-HIV-1 activity in vitro(see section 4.5) and was additive to antagonistic with the protease inhibitor ritonavir or the fusion inhibitor enfuvirtide.
Consider doubling the rifabutin dose in regimens where rifabutin is given 2 or3 times a week in combination with efavirenz.
When used in combination with efavirenz and two NRTIs, 533/ 133 mg lopinavir/ ritonavir(soft capsules) twice daily yielded similar lopinavir plasma concentrations as compared to lopinavir/ ritonavir(soft capsules) 400/ 100 mg twice daily without efavirenz(historical data).
Increase in the dose of both atazanavir and ritonavir to 400 mg and 200 mg, respectively, in combination with efavirenz could be considered with close clinical monitoring.
Efavirenz: when used in combination with efavirenz and two nucleoside reverse transcriptase inhibitors in multiple protease inhibitor-experienced patients, increasing the dose of Kaletra 33.3% from 400/ 100 mg(3 capsules) twice daily to 533/ 133 mg(4 capsules) twice daily yielded similar lopinavir plasma concentrations as compared to historical data of Kaletra 400/ 100 mg(3 capsules) twice daily.
They were randomised to receive either abacavir 600 mg once daily or300 mg twice daily, in combination with efavirenz and lamivudine given once daily.
Patients were randomised to 12 weeks of INCIVO(750 mg every 8 hours if taken in combination with atazanavir/ritonavir, tenofovir disoproxil fumarate, and emtricitabine or lamivudine OR1,125 mg every 8 hours if taken in combination with efavirenz, tenofovir disoproxil fumarate, and emtricitabine) or placebo.
Increase in the dose of both atazanavir and ritonavir to 400 mg and 200 mg, respectively, in combination with efavirenz could be considered with close clinical monitoring.
Along with nucleoside reverse transcriptase inhibitors(NRTIs), in some studies,KALETRA was used in combination with efavirenz or nevirapine.
The benefit of the combination of abacavir and lamivudine as a once daily regimen is mainly based on a study performed in combination with efavirenz, in antiretroviral-naïve adults patients(see section 5.1).
The following table contains dosing guidelines for Kaletra tablets based on BSA when used in combination with efavirenz or nevirapine in children.
The following table contains dosing guidelines for lopinavir/ritonavir tablets based on BSA when used in combination with efavirenz or nevirapine in children.
If the co-administration of REYATAZ with an NNRTI is required, an increase in the dose of both REYATAZ and ritonavir to 400 mg and200 mg, respectively, in combination with efavirenz could be considered with close clinical monitoring.
If the co-administration of atazanavir with an NNRTI is required, an increase in the dose of both atazanavir and ritonavir to 400 mg and200 mg, respectively, in combination with efavirenz could be considered with close clinical monitoring.
Efavirenz in combination with darunavirmay result in sub-optimal darunavir Cmin.
Both medicines were taken in combination with didanosine and efavirenz(other antiviral medicines).
Efavirenz in combination with darunavir/ritonavir 800/100 mg once daily may result in suboptimal darunavir Cmin.
The most notable unwanted effects reported with efavirenz in combination with other anti-HIV medicines are skin rash and nervous system symptoms.
Treatment with efavirenz in combination with amprenavir and saquinavir is not recommended, as the exposure to both protease inhibitors would be decreased.
Co-administration of efavirenz and atazanavir in combination with ritonavir may lead to increases in efavirenz exposure which may worsen the tolerability profile of efavirenz. .
ACTG 5202 study was a, multi-centre, comparative,randomised study of double-blind abacavir/lamivudine or emtricitabine/tenofovir in combination with open-label efavirenz or atazanavir/ritonavir in treatment-naïve HIV-1 infected patients.
When taken in combination with lamivudine and efavirenz, around 70% of the patients taking Zerit had viral loads below 400 copies/ml after 48 weeks.
One study compared the effects of Ziagen taken once andtwice a day, in combination with lamivudine and efavirenz(other antiviral medicines) in 784 patients.