Примери за използване на Gmcs на Английски и техните преводи на Български
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The very large and massive molecular clouds are called Giant Molecular Clouds(GMCs).
The antibody GMCs and OPA GMTs were lower after 2-dose for most vaccine serotypes.
For the cross-reactive serotype 19A, the results did not suggest any differences in ELISA antibody GMCs and OPA GMTs between groups.
In general, serotype-specific IgG GMCs were lower for preterm infants than term infants.
Pneumococcal immune responses were compared using non-inferiority criteria, including the percentage of subjects withserum anti-polysaccharide serotype-specific IgG concentration≥0.35 μg/ml and the comparison of IgG GMCs one month after the infant series.
After the booster dose the GMCs elicited by Synflorix were lower for most serotypes in common with 7-valent Prevenar.
The immune responses of the co-administered vaccines were unaffected,with the exception of lower geometric mean concentrations(GMCs) for one of the pertussis antigens(pertactin) when Shingrix is co-administered with the dTpa vaccine.
Pre-booster GMCs(8 to 12 months after the last primary dose) were generally similar for the two vaccines.
After the first dose, Prevenar 13 elicited antibody levels,measured by both IgG GMCs and OPA GMTs that were statistically significantly higher when compared to levels prior to vaccination.
In addition, GMCs were lower for antibodies to most serotypes after a twodose infant series than after a three-dose infant series.
The booster dose of Synflorix in HIV+/+ and HIV+/- infants induced robust increases in ELISA antibody GMCs and OPA GMTs for each vaccine serotype and serotype 19A indicative of immunological priming.
Similar antibody GMCs and OPA GMTs were observed for all infants except a lower OPA GMT for serotype 5 in very preterm infants.
A clinical study conducted in India assessing a booster dose given at 9-12 or 15-18 months of age in 66 and 71 children, respectively, following primary vaccination at 6, 10 and 14 weeks of age,did not suggest differences between groups in terms of antibody GMCs.
Immune responses as measured by IgG GMCs were assessed in 168-211 evaluable subjects approximately 1 month after vaccination.
One month after co-administration with a combined tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine, adsorbed(Tdap)in subjects aged 9 to 25 years, lower GMCs were observed to each pertussis antigen(pertussis toxoid[PT], filamentous haemagglutinin[FHA] and pertactin[PRN]).
One year after the second dose,antibody levels measured by both IgG GMCs and OPA GMTs were higher than levels prior to the first dose of Prevenar 13, except for the IgG GMCs for serotypes 3 and 5 that were numerically similar.
In these two studies pneumococcal immune responses were compared using a set of non-inferiority criteria including the percentage of subjects withserum anti-polysaccharide serotype-specific IgG≥ 0.35 μg/ml one month after the primary series and the comparison of IgG geometric mean concentrations(ELISA GMCs); in addition, functional antibody titres(OPA) between subjects receiving Prevenar 13 and Prevenar were compared.
Regarding PT and FIM,similar response rates and higher GMCs were observed both post-primary and post-booster in comparison to control vaccine.
OPA GMTs were observed for all infants except lower antibody GMCs for serotypes 4, 5, 9V and the cross-reactive serotype 19A in very preterms and serotype 9V in preterms and lower OPA GMT for serotype 5 in very preterms.
In the second clinical study,a single dose administered four months after two catch-up doses at 12-20 months of age elicited a marked increase of ELISA GMCs and OPA GMTs(when comparing the responses pre and post the last dose), indicating that two catch-up doses provide adequate priming.
Post-primary antibody geometric mean concentrations(GMCs) elicited by Synflorix against the seven serotypes in common were lower than those elicited by 7-valent Prevenar.
The third clinical study showed that the administration of 2 doses with a 2 month interval starting at 36-46 months of age resulted in higher ELISA antibody GMCs and OPA GMTs than those observed one month after a 3-dose primary vaccination for each vaccine serotype and the cross-reactive serotype 19A.
One month after the booster dose increases of ELISA antibody GMCs and OPA GMTs were seen for each vaccine serotype and the cross-reactive serotype 19A, indicative of immunological memory.
One month after co-administration with a 10-valent pneumococcal conjugate vaccine, lower Geometric Mean antibody Concentrations(GMCs) and opsonophagocytic assay(OPA) antibody GMTs were observed for one pneumococcal serotype(18C conjugated to tetanus toxoid carrier protein).