Примери за използване на Guanosine на Английски и техните преводи на Български
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The guanine nucleoside is called guanosine.
Guanosine triphosphate is essential for protein synthesis.
GTP: Magnesium is a cofactor for the enzyme guanosine triphosphatase(GTPase).
Cyclic guanosine monophosphate or cGMP helps arteries relax, which could increase blood flow to the penis.
Down a substance known as cyclic guanosine monophosphate(cGMP).
This enzyme synthesizes cyclic guanosine monophosphate(cGMP) from guanosine triphosphate(GTP) keeping cGMP-gated ion channels open, allowing calcium to enter the cell.
This causes an enzyme,guanylate cyclase, to produce cyclic guanosine monophosphate(cGMP).
Sildenafil is a potent andselective inhibitor of cyclic guanosine monophosphate(cGMP) specific phosphodiesterase type 5(PDE5), the enzyme that is responsible for degradation of cGMP.
The latter, in turn, stimulates an increase in the concentration of cGMP( cyclic guanosine monophosphate).
Tadalafil is a selective,reversible inhibitor of cyclic guanosine monophosphate(cGMP)-specific phosphodiesterase type 5(PDE5).
Linaclotide(Linzess) makes the intestines to produce more fluid by increasing the production of cyclic guanosine monophosphate.
Activation of GC-C results in an increase in concentrations of cyclic guanosine monophosphate(cGMP), both extracellularly and intracellularly.
Tadalafil is a potent and selective inhibitor of phosphodiesterase type 5(PDE5),the enzyme responsible for the degradation of cyclic guanosine monophosphate(cGMP).
When the enzyme is blocked,a substance called‘cyclic guanosine monophosphate'(cGMP) cannot be broken down and remains in the vessels where it causes widening of the blood vessels.
When NO binds to sGC,the enzyme catalyses synthesis of the signalling molecule cyclic guanosine monophosphate(cGMP).
Entecavir, a guanosine nucleoside analogue with activity against HBV polymerase, is efficiently phosphorylated to the active triphosphate(TP) form, which has an intracellular half-life of 15 hours.
Avanafil is a highly selective and potent,reversible inhibitor of cyclic guanosine monophosphate(cGMP)-specific phosphodiesterase type 5.
Mechanism of action:entecavir, a guanosine nucleoside analogue with activity against HBV polymerase, is efficiently phosphorylated to the active triphosphate(TP) form, which has an intracellular half-life of 15 hours.
It activates the enzyme guanylate cyclase,resulting in an increased level of cyclic guanosine monophosphate(cGMP) in the corpus cavernosum.
When the enzyme is blocked,a substance called‘cyclic guanosine monophosphate'(cGMP) cannot be broken down and remains in the vessels where it causes the relaxation and widening of the blood vessels.
It works by blocking the phosphodiesterase enzyme,which normally breaks down a substance known as cyclic guanosine monophosphate(cGMP).
Nitric oxide then activates the enzyme guanylate cyclase,which results in increased levels of cyclic guanosine monophosphate(cGMP), producing smooth muscle relaxation in the corpus cavernosum and allowing inflow of blood.
It works by blocking the phosphodiesterase enzyme,which normally breaks down a substance known as cyclic guanosine monophosphate(cGMP).
Nitric oxide then activates the enzyme guanylate cyclase,which results in increased levels of cyclic guanosine monophosphate(cGMP), producing smooth muscle relaxation in the corpus cavernosum and allowing inflow of blood.
Although any type of alcohol inhibits uric acid secretion and should be avoided in patients with gout,beer is a“double hit” because it is rich in guanosine, which adds to the body's purine load.
In particular, it has long been known that such components as nucleotides- adenosine, guanosine and uridine- have an exciting or depressing effect on the nervous system of the child, causing a healthy dream, or, conversely, anxiety.
It relaxes vascular smooth muscle by binding to the haeme moiety of cytosolic guanylate cyclase, activating guanylate cyclase andincreasing intracellular levels of cyclic guanosine 3', 5'-monophosphate, which then leads to vasodilation.
Consistent with its known effects on the nitric oxide/cyclic guanosine monophosphate(cGMP) pathway(see section 5.1), sildenafil was shown to potentiate the hypotensive effects of nitrates, and its co-administration with nitric oxide donors(such as amyl nitrite) or nitrates in any form is therefore contraindicated.
They found that a protein called Ryh1,when bound to another molecule called guanosine triphosphate, is needed to activate TORC 2.
Consistent with its known effects on the nitric oxide/ cyclic guanosine monophosphate(cGMP) pathway(see section 5.1), sildenafil was shown to potentiate the hypotensive effects of nitrates, and its co-administration with nitric oxide donors(such as amyl nitrite) or nitrates in any form is therefore contraindicated.