Примери за използване на Intestinal stem на Английски и техните преводи на Български
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Rescuing intestinal stem cells from attack in type 1 diabetes.
They used a molecule called FexD, developed at Salk,to activate FXR in intestinal stem cells.
Intestinal stem cells are responsible for maintaining the lining of the intestine, which typically renews itself every 5 days.
Researchers have been able to reverse the age-related loss of functionality in intestinal stem cells in a very simple way.
Intestinal stem cells, in turn, are essential to ensure the ongoing ability of the intestine to regenerate from damage and disease.
In this line of investigation, we focused on understanding how a 24-hour fast enhances the function of young and old intestinal stem cells.”.
Supporting this hypothesis,scientists have found that skin and intestinal stem cells are more susceptible to becoming tumors than other cells in those organs.
Paneth cells play an important role in protecting the intestine from damage by microbes,as well as maintaining healthy populations of intestinal stem cells.
Among the lab's discoveries was the revelation that bile acids send hormonal signals to intestinal stem cells through a protein called the Farnesoid X receptor(FXR).
In this line of investigation, we focused on understanding how a 24-hour fast enhances the function of young and old intestinal stem cells.”.
Researchers say their study is the first to indicate that intestinal stem cells- which allow different intestinal cell types to renew themselves- age as people do.
Intestinal stem cells rejuvenate daily so bowels will stay healthy and function normally, but a new study in Cell Reports suggests they also age along with people and lose their regenerative capacity.
We knew that high-fat diets and bile acids were both risk factors for cancer, butwe weren't expecting to find they were both affecting FXR in intestinal stem cells,” noted Annette Atkins, PhD, a staff researcher at Salk and co-author of the study.
According to an announcement about the study, scientists administered human-equivalent doses of chemotherapy drugs to Drosophila, a type of fruit fly, that had been spawned with a human cancer-causing gene,which activated in the flies' intestinal stem cells.
Reporting their data online March 14,researchers suggest that reactivating the signaling of a key molecule lost in aging intestinal stem cells could restore healthy intestinal function in older people.
It also is the first to provide clear evidence that diminished signaling in intestinal stem cells(ISCs) by the Wnt protein- which is important to cell proliferation and renewal- drives the aging process and loss of ISCs' ability to rejuvenate intestinal tissues.
Notably, during aging, intestinal stem function declines, which impairs the ability of the intestine to repair itself after damage,” senior author professor Omer Yilmaz, from MIT's Koch Institute for Integrative Cancer Research, said in a statement.
Deterioration of Wnt signaling in aging intestinal stem cells may help explain imbalances in food and nutrient absorption in older people, but our paper also shows that biology allows us to reverse this process by restoring Wnt signaling,” said Hartmut Geiger, PhD, senior investigator of the study.
But unlike stem cells in the blood or intestinal lining, hair follicle stem cells regenerate on a cyclical basis.
Separately, James Wells andcolleagues at Cincinnati Children's Hospital Medical Center in Ohio turned two different kinds of stem cell into complex layers of intestinal tissue.
A new study carried out by a team led by Professor Heiko Hermeking at the Institute of Pathology at LMU(and German Cancer Consortium)now shows that c-MYC induces the production of a transcription factor that increases the numbers of stem cells in the intestinal epithelium, and thereby contributes to the formation of adenomas in the colon.
A new study carried out by a team led by Professor Heiko Hermeking at the Institute of Pathology at LMU(and German Cancer Consortium) shows that the regulatory protein c-MYC, which plays an important role in promoting the development of many types of tumours,induces the production of a transcription factor that increases the numbers of stem cells in the intestinal epithelium, and thereby contributes to the formation of adenomas in the colon.
The study was conducted in mice and human intestinal organoids by scientists at Cincinnati Children's Hospital Medical Center and the Institute for Molecular Medicine, Stem Cells and Aging at the University of Ulm in Germany.
In adult organisms, stem cells act as a repair system for the body, replenishing specialized cells, but also maintain the normal turnover of blood, skin, and intestinal tissues.
In adult organisms, stem cells and progenitor cells act as a repair system for the body, replenishing specialised cells, but also maintain the normal turnover of regenerative organs, such as blood, skin or intestinal tissues.
The control mice showed that URI is expressed in a specific dormant stem cell population located in the intestinal crypts(called crypts of Lieberkühn).
This virus affects the rapidly dividing blood cells in the body,primarily the cells in the intestinal tract, bone marrow, and in the stem cells of the developing fetus.
Arbutin, which is obtained from the leaves and stems, is used by the pharmaceutical industry in preparations used to treat intestinal disorders.