Примери за използване на Known to inhibit на Английски и техните преводи на Български
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Drugs of this class are known to inhibit the cytochrome P450 system, ZA4.
Turmeric also promote cognitive health by inhibiting the buildup of beta amyloid,a peptide known to inhibit cognition.
This protein is known to inhibit the growth of tissues, including hair follicles.
Grapefruit products, including grapefruit juice andother foods that are known to inhibit CYP3A should be avoided(see section 4.5).
It was known to inhibit the formation of DHT, a major contributor to both prostate cancer and male pattern hair loss.
This may be, for example, a protective layer of silver microparticles, releasing silver ions into the air,which is known to inhibit microbial growth.
The co-administration of agents known to inhibit T-cell function has not been formally studied.
While taxol is known to inhibit ordinary cancer cells(and cause a host of awful side effects) it still struggles to eliminate cancer stem cells.
No dose adjustment for Zejula is required when administered concomitantly with medicinal products known to inhibit P-gp(e.g. amiodarone, verapamil) or BCRP(e.g. osimertinib, velpatasvir, and eltrombopag).
Concomitant use of substances known to inhibit or induce CYP3A4 may affect the metabolism of tacrolimus and thereby increase or decrease tacrolimus blood levels.
No dose adjustment for Zejula is required when administered concomitantly with medicinal products known to inhibit OATP1B1 or 1B3(e.g. gemfibrozil, ritonavir), or OCT1(e.g. dolutegravir) uptake transporters.
Other drugs known to inhibit CYP3A4, such as ketoconazole and erythromycin, might inhibit the metabolism of tramadol(N-demethylation) probably also the metabolism of the active O-demethylated metabolite.
Theoretically the metabolism of toremifene is inhibited by drugs known to inhibit the CYP3A enzyme system which is reported to be responsible for its main metabolic pathways.
Since bupropion is extensively metabolised, caution is advised when naltrexone/ bupropion is co-administered with medicinal products known to inhibit metabolism(e.g. valproate), as these may affect its clinical efficacy and safety.
As with other medicinal products known to inhibit prostaglandin synthesis, fluid retention and oedema have been observed in patients taking celecoxib.
Hence, in patients already receiving ropinirole,the dose of ropinirole may need to be adjusted when medicinal products known to inhibit CYP1A2, e.g. ciprofloxacin, enoxacin, cimetidine or fluvoxamine.
Red Yeast Rice comes from China,substances known to inhibit cholesterol synthesis, the ratio of Monacolin K of our product ranges from 0.4% to 1.5%.
As etoposide phosphate is converted in vivo to etoposide by phosphorylation,caution should be exercised when administering etoposide phosphate with drugs that are known to inhibit phosphatase activity as such combination may reduce efficacy of etoposide phosphate.
As with other medicinal products known to inhibit prostaglandin synthesis, fluid retention and oedema have been observed in some patients taking parecoxib.
No dose adjustment for Zejula is required when administered concomitantly with medicinal products known to inhibit(e.g. itraconazole, ritonavir, and clarithromycin) or induce CYP enzymes(e.g. rifampin, carbamazepine, and phenytoin).
Use of ophthalmic topical agents known to inhibit epithelial healing, including corticosteroids or eye drops containing preservatives such as benzalkonium chloride, polyquaternium-1, benzododecinium bromide, cetrimide and other quaternary ammonium derivatives, should be avoided during treatment of neurotrophic keratitis, as they could interfere with corneal healing(see section 4.5).
No dose adjustment for Zejula is required when administered concomitantly with medicinal products known to inhibit OAT1(e.g. probenecid) or OAT3(e.g. probenecid, diclofenac), or OCT2(e.g. cimetidine, quinidine) uptake transporters.
Levonorgestrel(LGN) is a progestogen known to inhibit ovulation, whilst the low dose ethinylestradiol(EE), an estrogen, ensures control over ovarian follicular suppression and provides stability to the endometrium in order to minimise breakthrough bleeding.
The potential for drug-drug interactions should be borne in mind when[Product name]is coadministered with drugs known to inhibit or induce drug metabolising enzymes or drugs known to be substrates for renal carrier mechanisms.
As with other medicinal products known to inhibit prostaglandin synthesis, fluid retention, oedema and hypertension have been observed in patients taking etoricoxib.
Fluid retention, oedema andhypertension As with other medicinal products known to inhibit prostaglandin synthesis, fluid retention, oedema and hypertension have been observed in patients taking etoricoxib.
Concomitant use of medicinal products known to inhibit lipase should be given with caution as glycerol phenylbutyrate is hydrolysed by digestive lipase into phenylbutyrate acid and glycerol.
Therefore, caution is recommended when bictegravir is combined with medicinal products known to inhibit P-gp and/or BCRP(e.g. macrolides, ciclosporin, verapamil, dronedarone, glecaprevir/pibrentasvir)(see also table below).
The use of Dynastat,as with any medicinal product known to inhibit cyclooxygenase/ prostaglandin synthesis, is not recommended in women attempting to conceive(see sections 4.6 and 5.1).
Therefore, caution should be exercised when administering paclitaxel concomitantly with medicines known to inhibit(e. g. erythromycin, fluoxetine, imidazole antifungals) or induce(e. g. rifampicin, carbamazepine, phenytoin, efavirenz, nevirapine) either CYP2C8 or CYP3A4.