Примери за използване на Large volume of distribution на Английски и техните преводи на Български
{-}
-
Medicine
-
Colloquial
-
Official
-
Ecclesiastic
-
Ecclesiastic
-
Computer
Non-liposomal irinotecan displays a large volume of distribution(138 l/m2).
It has a large volume of distribution(range of means 43 to 114 l/m2).
Ranitidine is not extensively bound to plasma proteins(15%),but exhibits a large volume of distribution ranging from 96 to 142 L.
Pixuvri has a large volume of distribution of 25.8 l and is approximately 50% bound to plasma proteins.
Pharmacokinetic parameters observed for piperaquine in humans indicate that this active substance has a large volume of distribution(730 l/kg; CV 37.5%).
Duloxetine has a large volume of distribution and forced diuresis, haemoperfusion, and exchange perfusion are unlikely to be beneficial.
Haloperidol is rapidly distributed to various tissues and organs,as indicated by the large volume of distribution(mean values 8 to 21 l/kg after intravenous dosing).
Duloxetine has a large volume of distribution and forced diuresis, haemoperfusion, and exchange perfusion are unlikely to be beneficial.
Fentanyl is rapidly distributed to various tissues and organs,as indicated by the large volume of distribution(3 to 10 L/kg after intravenous dosing in patients).
Due to the large volume of distribution of paroxetine, forced diuresis, dialysis, hemoperfusion and exchange transfusions are unlikely to be of benefit.
Dialysis studies have not been performed, however, due to the large volume of distribution, dialysis is unlikely to be an effective treatment for Aloxi overdose.
The large volume of distribution indicates extensive extravascular distribution and/or tissue binding of paclitaxel.
Dialysis studies have not been performed, however, due to the large volume of distribution, dialysis is unlikely to be an effective treatment for palonosetron overdose.
However, due to the large volume of distribution of palonosetron and netupitant, dialysis is unlikely to be an effective treatment for overdose.
The disposition of fluticasone propionate is characterised by high plasma clearance(1150 mL/min), a large volume of distribution at steady-state(approximately 300 L) and a terminal half-life of approximately 8 hours.
Due to the large volume of distribution of sertraline, forced diuresis, dialysis, haemoperfusion and exchange transfusion are unlikely to be of benefit.
Based on venetoclax large volume of distribution and extensive protein binding, dialysis is unlikely to result in significant removal of venetoclax.
Based on population pharmacokinetic analysis, the total volume of distribution is approximately 1741 L; the large volume of distribution indicates extensive extravascular distribution and/or tissue binding of paclitaxel.
The low total body clearance and large volume of distribution resulted in a terminal elimination half-life in plasma of approximately 40 hours.
The apparent volume of distribution of amprenavir following administration of Telzir is approximately 430 l(6 l/kg assuming a 70 kg body weight),suggesting a large volume of distribution, with penetration of amprenavir freely into tissues beyond the systemic circulation.
Asenapine is rapidly distributed and has a large volume of distribution(approximately 20-25 L/kg), indicating extensive extravascular distribution. .
The mean volume of distribution was 632 l/ m2; the large volume of distribution indicates extensive extravascular distribution and/ or tissue binding of paclitaxel.
Infants and children had higher clearance, larger volume of distribution, shorter half-life and lower recovery than adolescents and adults.
Furthermore, its lipophilicity is higher compared to the other ARB,which implies a larger volume of distribution and a better penetration into tissues.
After adjusting for BSA,male subjects had a larger volume of distribution and a faster clearance than female subjects.
Telmisartan also has the highest lipophilicity compared to other sartans that provides the largest volume of distribution and facilitate its penetration in various organs and tissues.
Plasma concentrations after treatment with EMLA are 20-60% lower for prilocaine than for lidocaine, because of a larger volume of distribution and more rapid clearance.
The volume of distribution is large, indicating extensive tissue distribution and intracellular uptake.
In healthy volunteers, pasireotide is widely distributed with large apparent volume of distribution(Vz/F> 100 litres).