Примери за използване на Leukaemic на Английски и техните преводи на Български
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SPRYCEL inhibits the growth of these leukaemic cells.
C MRD negativity was defined by flow cytometry as leukaemic cells comprising< 1× 10-4(< 0.01%) of bone marrow nucleated cells.
Vyxeos liposomal may induce hyperuricemia secondary to rapid lysis of leukaemic cells.
In vitro, dasatinib is active in leukaemic cell lines representing variants of imatinib-sensitive and resistant disease.
Our work could also be beneficial to a broad range of solid cancers and leukaemic malignancies with elevated SALL4.".
The immediate cell death of leukaemic cells in vivo, measured by rhodamine fluorescence, was the same for all three L-asparaginase preparations.
Then, donor immune cells are transplanted with and after the donor HSCs to attack andeliminate any remaining leukaemic cells.
Exposure to cladribine induces DNA fragmentation andcell death in various normal and leukaemic cells and cell lines at concentrations of 5 nM to 20 µM.
Instead, donor immune cells are transplanted with the donor haematopoietic stem cells to attack andeliminate any remaining leukaemic cells.
Complete remission(CR) was defined as the absence of visible leukaemic cells in the bone marrow and peripheral recovery of platelets and white blood cells.
Saturation of a high percentage of CD33 antigenic sites is presumed to be required for maximum delivery of calicheamicin to leukaemic blast cells.
We have found that the leukaemic cell has an altered cell surface carbohydrate decoration compared to normal cells and this also conveys resistance to drug treatment," Professor von Itzstein said.
TRISENOX was administered intravenously over 1 to 2 hours until the bone marrow was free of leukaemic cells, up to a maximum of 60 days.
A major cytogeneticresponse is defined by< 34% Ph+ leukaemic cells in the bone marrow, whereas a minor response is 34%, but< 90% Ph+ cells in the marrow.
High doses of chemotherapy agents given to leukaemia patients before a transplant destroys both leukaemic cells and healthy bone marrow cells.
The role of Ceplene is to protect lymphocytes, in particular NK cells and T cells,which are responsible for the immune-mediated destruction of residual leukaemic cells.
For the purpose of haematopoietic stem cell mobilisation,plerixafor may cause mobilisation of leukaemic cells and subsequent contamination of the apheresis product.
TRISENOX must be administered intravenously at a fixed dose of 0.15 mg/kg/day given daily until complete remission is achieved(less than 5% blasts present in cellular bone marrow with no evidence of leukaemic cells).
Such transplants are effective because they contain important immune cells that help to kill the leukaemic cells in addition to different subpopulations of HSCs that rescue blood production at different rates.
It is currently unclear whether long-term treatment of patients with SCN will predispose patients to cytogenetic abnormalities,MDS or leukaemic transformation.
Midostaurin inhibits FLT3 receptor signalling andinduces cell cycle arrest and apoptosis in leukaemic cells expressing FLT3 ITD or TKD mutant receptors or over-expressing FLT3 wild type receptors.
It is currently unclear whether long-term treatment of patients with SCN will predispose patients to cytogenetic abnormalities,MDS or leukaemic transformation.
In an open-label non-comparative dose escalation study in 18 paediatric patients(4 to 19 years) with leukaemic meningitis or neoplastic meningitis due to primary brain tumour, an intrathecal dose of 35 mg was identified as the maximum tolerated dose.
Patients with newly diagnosed APL confirmed by the presence of t(15; 17) or PML-RARα by RT-PCR ormicro speckled PML nuclear distribution in leukaemic cells were included.
The high dose of chemotherapy given to leukaemia patients before a transplant is destructive to both the leukaemic cells and the patient's healthy bone marrow cells.
The intracellular retention time of cladribine nucleotides in vivo is clearly prolonged as compared to the retention time in the plasma: Half-lives t1/2 of initially 15 hours and subsequently more than 30 hours were measured in leukaemic cells.
Ceplene/IL-2 is an immunotherapy which aims to induce immune-mediated destruction of residual myeloid leukaemic cells and thereby to prevent relapse of leukaemia.
TRISENOX must be administered intravenously at a fixed dose of 0.15 mg/ kg/ day given daily until the bone marrow remission is achieved(less than 5% blasts present in cellular bone marrow with no evidence of leukaemic cells).
Retroviral insertion sites(RIS) have been detected adjacent to or within CCND2 and LMO2 andthere is a potential risk of leukaemic transformation following treatment with Strimvelis.