Примери за използване на Metabolic profile на Английски и техните преводи на Български
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Metabolic profile of tipranavir.
Interactions linked to dabigatran etexilate and dabigatran metabolic profile.
Based on known metabolic profiles, clinically significant interactions are not expected between.
Athletes choose a diet full of protein because it helps with weight management and improves our metabolic profile.
The complete metabolic profile of delamanid in man has not yet been fully elucidated(see sections 4.5 and 5.2).
This assumption is supported by the results of an ex-vivo studywhich compared pig and rabbit liver metabolic profiles.
The complete metabolic profile and mode of elimination of delamanid has not yet been fully elucidated(see sections 4.4 and 5.2).
There's no universal definition of metabolic health in obese people, but researchers estimate that between 25 percent and30 percent of the obese have normal metabolic profiles.
I-bevacizumab indicated that its metabolic profile was similar to that expected for a native IgG molecule which does not bind VEGF.
Due to its vasodilatory effect(and unlike older beta-1 selective BB), nebivolol does not lead to the deterioration of insulin sensitivity andan increased risk of type 2 diabetes(neutral metabolic profile).
However, other studies have shown no improvements in the metabolic profiles of dieters who took supplements containing both calcium and vitamin D(6).
Based on known metabolic profiles, clinically significant interactions are not expected between Kaletra and fluvastatin, dapsone, trimethoprim/ sulfamethoxazole, azithromycin or fluconazole.
Assessment of bevacizumab metabolism in rabbits following a single IV dose of 125I-bevacizumab indicated that its metabolic profile was similar to that expected for a native IgG molecule which does not bind VEGF.
Since fluoxetine shares a similar metabolic profile with paroxetine, i. e. a strong CYP2D6 inhibitory effect, a similar lack of interaction would be expected for fluoxetine.
Janiszewski, who blogs about obesity research on the Public Library of Science website,added that metabolically healthy obese individuals are usually more active than those who are obese with poor metabolic profiles.
Since fluoxetine shares a similar metabolic profile with paroxetine, i.e. a strong CYP2D6 inhibitory effect, a similar lack of interaction would be expected for fluoxetine.
However, a number of studies have demonstrated that some obese individuals have lower cardiovascular risk and an improved metabolic profile, while a subset of"normal-BMI" people are metabolically unhealthy and have increased mortality risk.
For example, if we compare the metabolic profile of those with severe heart disease to those with clean arteries, maybe we could come up with a cheap, simple, noninvasive way to screen people.
There are other health benefits to sleeping in a colder room as well: in one study published in the journal Diabetes,men sleeping in a cooler room improved their metabolic profile and significantly reduced their chances of metabolic diseases like diabetes.
For example, if we compared the metabolic profile of those with severe heart disease to those with clean arteries, we might be able to come up with a cheap, simple, and noninvasive way to screen people.
Observation of phenotypic features only is often insufficient to this end, especially when dealing with transformed material,while the study of the chemical and metabolic profiles sometimes presents limits due to the part of the plant which is used, its stage of development, its origin or the professing the vegetable material underwent.
Due to their metabolic profile and inherent risk of inducing torsades de pointes, administration of halofantrine and lumefantrine with APTIVUS co-administered with low dose ritonavir, is not recommended.
In the absence of physiological similarity, a comparison of metabolic profile based on in vitro studies(e.g. performed in hepatocytes using labelled compound) is considered sufficient to assess metabolic proximity.
The complete metabolic profile of delamanid has not yet been elucidated, and there is a potential for drug interactions with other co-administered medications, if significant unknown metabolites are discovered.
The researchers said people with high anxiety traits had a distinct metabolic profile, and changes that occurred from eating dark chocolate showed up clearly after two weeks with reduced stress hormones and other stress-related biochemical markers.
Based on the metabolic profiles, a clinically relevant drug interaction would not be expected with other specific inhibitors of CYP3A(e. g., fluconazole, itraconazole, clarithromycin, erythromycin); however, the possibility cannot be excluded.
In young patients with recent diagnosis of T2DM, central obesity, and abnormal metabolic profile, one should consider treatment with GLP-1 analogs that would have a beneficial effect on weight loss and improve the metabolic dysfunction.
Based on the known metabolic profile of avatrombopag and the fact that only 6% of the dose is excreted in urine, the likelihood of effects of renal impairment on pharmacokinetics of avatrombopag is considered to be very low(see sections 4.2 and 4.8).
The method of administration; some studies used gavage administration(which improves the accuracy of the dose, but also(potentially)affects the metabolic profile of the substance, since this is in effect a bolus dose, rather than a continuous dose), some studies used drinking water administration, as specified in the SPCs(which could lead to more variable results due to some birds drinking more medicated water than others, but is more representative of what would happen‘in the field');
Regarding the metabolic profile of tolperisone the in vitro data which are discussed in the response document do not substitute for the in vivo interaction studies and do not allow conclusive on possible PK or PD drug-drug interactions.