Примери за използване на Milbemycin на Английски и техните преводи на Български
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Milbemycin oxime.
ATCvet code: QP54AB51(milbemycin combinations).
Milbemycin oxime acts as an‘endoparasiticide'.
Moxidectin is a second-generation macrocyclic lactone of the milbemycin family.
Milbemycin oxime contains two major factors, A3 and A4(ratio of 20:80 for A3:A4).
Pharmacotherapeutic group: antiparasitic products,endectocides, milbemycin combinations.
Milbemycin oxime is an antiparasitic endectocide belonging to the macrocyclic lactones.
The comparator was selamectin in cats, and milbemycin oxime and praziquantel in dogs.
Milbemycin oxime is isolated from the fermentation of Streptomyces hygroscopicus var. aureolacrimosus.
Laboratory studies(in rats andrabbits) on the effect of spinosad and milbemycin oxime have neither.
The second active substance, milbemycin oxime, causes paralysis and death of worms by interfering.
In clinical studies,no serious adverse reactions were attributed to the combination of afoxolaner with milbemycin oxime.
Milbemycin oxime acts by disrupting the glutamate neuro-transmission in invertebrates.
Salivation has been observed in dogs given higher dose multiples of milbemycin oxime alone(5 to 10 mg/kg).
The activity of milbemycin oxime is related to its action on invertebrate neurotransmission.
The safe use of the maximum recommended dose(70 mg/kg spinosad and 1.18 mg/kg milbemycin oxime) given as capsules has been demonstrated for 12 months.
Milbemycin oxime is an antiparasitic endectocide belonging to the group of macrocyclic lactones.
Dogs with gut worm infections were given either a single treatment with Nexgard Spectra ora medicine containing milbemycin oxime and praziquantel(another medicine for worms).
Milbemycin oxime increases glutamate binding with consequent enhanced chloride ion flow into the cell.
The study showed that Nexgard Spectra was effective in reducing gut worms andwas at least as effective as the milbemycin oxime and praziquantel.
Milbemycin oxime is a systemic macrocyclic lactone containing two major factors, A3 and A4(ratio of A3:A4 is 20:80).
In a field study involving dogs infected with roundworms or hookworms, 194 dogs were treated with Simparica Trio and97 dogs with afoxolaner and milbemycin oxime.
Milbemycin oxime plasma concentrations and some pharmacokinetic parameters are increased in the presence of spinosad.
In laboratory safety studies,no interactions were observed when sarolaner was co-administered with milbemycin oxime, moxidectin and pyrantel pamoate.
The mean Tmax for milbemycin A3 and A4 5-oximes was typically 4 hours and the mean elimination half-lives were 33.9 and 77.2 hours.
In laboratory safety studies,no interactions were observed when sarolaner was co-administered with milbemycin oxime, moxidectin and pyrantel pamoate.(In these studies efficacy was not investigated).
Milbemycin should be used with caution in ivermectin-sensitive breeds due to the potential of similar adverse effects.
The drugs approved for use in the US are ivermectin(sold under the brand names Heartgard, Iverhart, andseveral other generic versions), milbemycin(Interceptor Flavor Tabs and Sentinel Flavor Tabs) and moxidectin(ProHeart) administered as pills or chewable tablets.
Milbemycin oxime in the formulation is active against larvae and adult nematodes, which parasitize in the gastrointestinal tract of dogs.
The excretion of milbemycin oxime in lactating dogs(bitches) has not been tested and the safety for suckling puppies has not been established.