Примери за използване на Minor metabolites на Английски и техните преводи на Български
{-}
-
Medicine
-
Colloquial
-
Official
-
Ecclesiastic
-
Ecclesiastic
-
Computer
Two minor metabolites were also identified.
The remainder of the urinary recovery consists of minor metabolites.
Two minor metabolites of atazanavir in plasma have been characterised.
The remaining circulating radioactivity consisted of a number of minor metabolites.
Two minor metabolites, relative to paricalcitol, were detected in human plasma.
Approximately 28% of the urinary metabolites are unidentified minor metabolites.
Other minor metabolites accounted for 13.8% of the radioactivity in plasma.
C isavuconazonium sulfate in humans, in addition to the active moiety(isavuconazole) andthe inactive cleavage product, a number of minor metabolites were identified.
Minor metabolites due to glucuronidation and oxidation were also detected.
About 80% of the radioactivity recovered in feces is excreted during the first 48 hours as 1 major and 3 minor metabolites with very small amounts(< 8%) of unchanged drug.
Two major and six minor metabolites of regorafenib have been identified in plasma.
Based on the published literature, in vitro studies with human liver microsomes andtissue slices show that paclitaxel is metabolised primarily to 6α-hydroxypaclitaxel; and to two minor metabolites, 3'-p-hydroxypaclitaxel and 6α -3'-p-dihydroxypaclitaxel.
Minor metabolites in urine include varenicline N- carbamoylglucuronide and hydroxyvarenicline.
Systemic exposures to the major and minor metabolites in humans were approximately 50% and less than 1% that of azilsartan, respectively.
Minor metabolites in urine include varenicline N-carbamoylglucuronide and hydroxyvarenicline.
Additional minor metabolites are formed by glucuronidation, oxidation and hydrolysis.
The minor metabolites dexmedetomidine carboxylic acid, 3-hydroxymethyl dexmedetomidine and its Oglucuronide individually comprised 1.11 to 7.66% of the dose.
Of the four minor metabolites detected in urine, two are Phase I oxidative metabolites present in low concentrations.
At least 5 minor metabolites of paritaprevir have been identified in circulation that accounted for approximately 10% of plasma radioactivity.
Minor metabolites in plasma are Rlicarbazepine and oxcarbazepine, which were shown to be active, and the glucuronic acid conjugates of eslicarbazepine acetate, eslicarbazepine, R-licarbazepine and oxcarbazepine.
A glucuronide conjugate was seen as a minor metabolite in excreta only.
Naldemedine 3-G was a minor metabolite in plasma, with a relative exposure to naldemedine of less than 3%.
OH-loxapine is not pharmacologically active at the D2 receptor while the minor metabolite, 7-OH-loxapine, has high binding affinity to D2 receptors.
The reduced metabolite of opicapone(found to be active in non-clinical studies)is a minor metabolite in human plasma, and represented less than 10% of total systemic exposure to opicapone.
The major metabolite in plasma is formed by Odealkylation,referred to as metabolite M-II, and the minor metabolite is formed by decarboxylation, referred to as metabolite M-I.
In addition to the active metabolite, inactive metabolites are formed,including two major metabolites formed by hydroxylation of the butyl side chain and a minor metabolite, an N-2 tetrazole glucuronide.
Minor circulating metabolites include varenicline N-carbamoylglucuronide and N- glucosylvarenicline.
Renal clearance of abemaciclib and its metabolites is minor.
One major and several minor oxidative metabolites were found in plasma.