Примери за използване на Multiple mutations на Английски и техните преводи на Български
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Several genetic elements and multiple mutations are required.
In contrast, the many bioactive compounds of GSE are able to target multiple mutations.
Such an ability would require multiple mutations, which wouldn't occur all at once.
Resistance to moxifloxacin develops slowly by multiple mutations.
Such an ability would require multiple mutations, which don't just happen all at once.
Efficacy Atazanavir/ritonavir is not effective in viral strains harbouring multiple mutations of resistance.
For a cancer to develop efficiently,it needs multiple mutations to accumulate in the DNA of the cell that becomes the tumour's ancestor.
If getting cancer is purely bad luck,then intrinsic factors would be need to be sufficient to cause multiple mutations.
A new idea announced in 2011 is an extreme version of multiple mutations, called chromothripsisby its proponents.
Under this model, cancer arises as the result of a single, isolated event,rather than the slow accumulation of multiple mutations.
He went on:"The probability of having multiple mutations that would modify all the targeted receptors decreases dramatically with the number of targets used".
A study, published today in Cell, demonstrates the power of organoids to capture,in three dimensions, the multiple mutations that occur in tumours.
The probability of having multiple mutations that would modify all targeted receptors simultaneously decreases dramatically within the number of targets used".
Viral resistance to abacavir develops relatively slowly in vitro, requiring multiple mutations for a clinically relevant increase in EC50 over wild-type virus.
The probability of having multiple mutations that would modify all targeted receptors simultaneously decreases dramatically with the number of targets used,” Dr Morad said.
Viral resistance to abacavir develops relatively slowly in vitro,requiring multiple mutations for a clinically relevant increase in EC50 over wild-type virus.
The probability of having multiple mutations that would modify all targeted receptors simultaneously decreases dramatically with the number of targets used,”“Instead of attacking receptors one at a time, we attack receptors three at a time- not even cancer can mutate three receptors at the same time.”.
Early discontinuation of failingtherapies is recommended in order to limit the accumulation of multiple mutations, which may be detrimental to a subsequent rescue regimen.
Morad added-“The probability of having multiple mutations that would modify all targeted receptors simultaneously decreases dramatically with the number of targets used.
Early discontinuation of failingtherapies is recommended in order to limit the accumulation of multiple mutations, which may be detrimental to a subsequent rescue regimen.
Single mutations may not result in clinical resistance, but multiple mutations generally result in clinical resistance to many or all active substances within the class.
Somatic mutations can occur in multiple circumstances.
Genetic testing for Lynch syndrome is often part of a test for multiple cancer-related genetic mutations.
Simpson, one of the elite spokesmen for evolution,writes about multiple, simultaneous mutations and reports that the mathematical likelihood of getting good evolutionary results would occur only once in 274 billion years!
Mutations in the RET gene cause multiple endocrine neoplasia type 2(MEN 2), which is an autosomal dominant disorder associated with a high lifetime risk of MTC.[1].
Based on available virological and clinical data from adult patients,no benefit is expected in patients with strains resistant to multiple protease inhibitors(≥ 4 PI mutations).
Based on available virological and clinical data from adult patients, no benefit is expected in patients with strains resistant to multiple protease inhibitors(≥ 4 PI mutations).
Darwin was right if it is proven that matter evolves on the basis of multiple variations born out of mutations and the natural selection singles out the most appropriate forms and in this way leads to perfecting the physical, chemical and biological structures.
In the Phase III trials DUET-1 and DUET-2, mutations that developed most commonly in patients with virologic failure to the etravirine containing regimen were V108I, V179F, V179I, Y181C and Y181I,which usually emerged in a background of multiple other NNRTI resistance-associated mutations(RAMs).
In the Phase III trials DUET-1 and DUET-2, mutations that developed most commonly in patients with virologic failure to the INTELENCE containing regimen were V108I, V179F, V179I, Y181C and Y181I,which usually emerged in a background of multiple other NNRTI resistance-associated mutations(RAMs).