Примери за използване на Oncolytic на Английски и техните преводи на Български
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Several diseases have oncolytic(anti-cancer) properties.
Oncolytic virus therapy uses genetically modified viruses to kill cancer cells.
The active substance in Imlygic, talimogene laherparepvec,is a type of gene therapy called‘oncolytic virus'.
Oncolytic viruses can occur naturally or can be made in the laboratory by changing other viruses.
The active substance of Imlygic is talimogene laherparepvec, an oncolytic virus derived from HSV-1.
The oncolytic vector gene therapy is another contemporary branch in the treatment of prostate cancer.
Food and Drug Administration approved the first oncolytic virus therapy for melanoma, Amgen's Imlygic.
Oncolytic viruses occur naturally, but they can also be made in the laboratory by modifying other viruses.
Current technology is also limited in that it cannot yet produce large quantities of vaccine orcreate potent oncolytic viruses in high concentrations.
IDIBELL researchers have developed an oncolytic virus capable of redirecting the patient's immune system against their tumor cells.
Janssen has entered into a definitive agreement to acquire BeneVir Biopharm,a privately-held, biopharmaceutical company specializing in the development of oncolytic immunotherapies.
They found that the oncolytic viruses were much more effective at attacking cancer cells when there was less glucose around.
This is a good thing to assure they will not develop measles butwould be extremely problematic for measles oncolytic therapy- the patient's own antibody would kill off the killer measles before it could reach the cancer cell.
Oncolytic viruses specifically target and enter cells and use the cells‘ machinery for their own multiplication and spread.
Amgen's product portfolio and pipeline also includes many novel modalities, such as peptibodies, BiTE® antibody constructs, andother bispecific molecules, antibody-drug conjugates, and oncolytic immunotherapy.
In their work with oncolytic viruses, Dyer and his team decided to alter the laboratory conditions to better match those of real life.
Oncolytic viruses such as the coxsackievirus could transform the way we treat cancer and could signal a move away from more established treatments such as chemotherapy,” Nicola Annels, Research Fellow at the University of Surrey, said.
Just as with immunotherapy vaccines, oncolytic viral therapy can create a long-term, robust defense that trains the immune system to attack cancer over months, or even years.
We work with oncolytic adenoviruses, viruses that are modified to exclusively attack cancer cells without attacking normal tissue, like a targeted therapy", explains Carlos Fajardo, lead author of the study.
Current work at the OSUCCC-James using oncolytic viruses takes advantage of three categories of treatment- a virus, a cancer drug and an immunotherapy- to treat a deadly form of brain cancer called glioblastoma.
We work with oncolytic adenoviruses, which are viruses modified to attack cancer cells exclusively, without attacking normal tissue, as a targeted therapy," explains Carlos Fajardo, lead author of the study.
Using novel approaches to examine exactly how oncolytic viruses attack tumours, the new study- published in Cancer Research- provided surprising insights about how a viral infection can cooperate with the immune system to attack cancer cells.
It is believed that oncolytic viruses not only directly destroy the tumor cells, but they also stimulate the host anti-tumor immune responses.
First these viruses,called oncolytic viruses, can directly assault tumor cells, and they can also massively replicate within the diseased cells, causing them to violently explode.
SillaJen is developing an oncolytic viral therapy called Pexa-Vec, currently in phase III and phase Ib-II clinical trials for use against primary liver and colorectal cancers, respectively.
We matched a modified oncolytic herpes simplex virus with a drug called bortezomib(which slows tumor growth and boosts the impact of radiation and chemotherapy) and an immunotherapy, which in this case is an infusion of immune cells.
Researchers have been developing oncolytic viruses since the 1980s, but following the U.S. Food and Drug Administration's 2015 approval of Amgen's Imlygic(T-Vec)as the first oncolytic viral therapy in the U.S., such viruses have become a closely watched area of therapeutic development.
A new study has shown that a cancer-killing(‘oncolytic') virus currently in clinical trials may function as a cancer vaccine- in addition to killing some cancer cells directly, the virus alerts the immune system to the presence of a tumor, triggering a powerful, widespread immune response that kills cancer cells far outside the virus-infected region.
A new UC San Francisco study has shown that a cancer-killing("oncolytic") virus currently in clinical trials may function as a cancer vaccine- in addition to killing some cancer cells directly, the virus alerts the immune system to the presence of a tumour, triggering a powerful, widespread immune response that kills cancer cells far outside the virus-infected region.