Примери за използване на Suppressor genes на Английски и техните преводи на Български
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Tumor suppressor genes are typically split up into two types.
Key words: ovarian cancer; oncogenes;tumor suppressor genes.
Oncogenes and tumor suppressor genes, which cause the disease.
When active oxygenis generated it damages the oncogenes, tumor suppressor genes and.
Tumor suppressor genes are also involved in controlling cell growth and division.
Cells with certain alterations in tumor suppressor genes may divide in an uncontrolled manner.
Tumour Suppressor genes are normal genes that slow down cell growth and division.
Acquired mutations of oncogenes and/or tumor suppressor genes may result from radiation or cancer causing chemicals.
Tumor suppressor genes are genes that inhibit cell division, survival, or other properties of cancer cells.
In cancer cells, oncogenes act like a“stuck gas pedal”,and tumor suppressor genes act like“broken brakes”.
Other tumor suppressor genes that are thought to play a role in prostate cancer include PTEN(gene) and KAI1.
Penetrance can be caused by factors such as epistatic genes, modifier genes, suppressor genes, and possibly environmental factors.
Mutations in tumor suppressor genes like the BRCA genes are considered“high-penetrance” because they often lead to cancer.
The genetic changes that contribute to cancer tend to affect threemain types of genes-proto-oncogenes, tumor suppressor genes and DNA repair genes.
These acquired mutations of oncogenes and tumor suppressor genes may come from other factors like radiation or cancer-causing chemicals.
A well-known and potent tumor suppressive gene, PTEN is one of the most frequently mutated, deleted, down-regulated, orsilenced tumor suppressor genes in human cancers.
These acquired mutations of oncogenes and/or tumor suppressor genes may result from other factors, like radiation or cancercausing chemicals.
When tumor suppressor genes don't work properly, cells can grow out of control, make more cells that grow out of control, and don't die when they should, which can lead to cancer.
For example, a mutation limited to one oncogene would be suppressed by normal mitosis control and tumor suppressor genes, which was first hypothesised by the Knudson hypothesis.
The pathogenesis of BCC involves exposure to UVL, particularly the ultraviolet B spectrum(290 to 320 nm)that induces mutations in tumor suppressor genes.
These acquired mutations of oncogenes and/or tumor suppressor genes may result from other factors, such as radiation or cancer-causing chemicals.
Tumor suppressor genes are normal genes that slow down cell division and repair DNA mistakes or tell cells when to die(a process known as apoptosis or programmed cell death).
The research team found consistent associations with outcomes for two relatively common mutations in two tumor suppressor genes called MAP3K1 and TP53, which had opposing effects.
Tumor suppressor genes: These are normal genes that slow down cell division, repair DNA errors, and tell cells when to die(a process known as apoptosis or programmed cell death).
A well-known and potent tumor suppressive gene, PTEN is one of the most frequently mutated, deleted, down-regulated, orsilenced tumor suppressor genes in human cancers.
Tumour suppressor genes are normal genes that slow cell growth and division, repair mistakes in DNA and tell cells when to die(a normal process called apoptosis or programmed cell death).
Histone deacetylases are enzymes that can literally switch off entire regions of DNA,including tumor suppressor genes, which is what often contributes very heavily to uncontrolled cell growth in most cancers.
The researchers found that people with autism had a greater enrichment of rare, coding variants within oncogenes- genes that have cancer-causing potential- than those without autism, butsuch enrichment was not identified in tumor suppressor genes.
The research team reports consistent associations with outcomes for two relatively common mutations in two tumor suppressor genes, MAP3K1 and TP53, which had opposing effects- MAP3K1 is associated with favorable outcomes, and TP53 with poor prognosis.
This idea that we have tumor suppressor genes goes back to famous research in the 60s that showed that if you fuse together a normal cell with a cancer cell, the cancer cell doesn't turn the normal cell malignant.