Примери за използване на The ligand на Английски и техните преводи на Български
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The ligand is made by fusing a fatty acid with another peptide.
The ligand was shown to extend the effectiveness of the peptide by several hours, inhibiting the disease in rabbits.
Biological effects of the soluble forms of the ligands DELTA1 and JAGGED1 in cellular signalization by NOTCH receptors, 2005.
These genes are biochemically linked: PDGFRB encodes the platelet-derived growth factor receptor β andPDGFB encodes the ligand of PDGF-Rβ.
Manganese and the ligand(fodipir), which have different pharmacokinetics, are eliminated by different routes.
A ligand is an ion ormolecule that binds to the metal atom to form a complex and the ligand usually gives one or more electrons connections.
They then appended the ligand to an actual peptide developed to treat pathogenic thrombosis, which has a notoriously impractical short half-life.
Panitumumab binds to the ligand binding domain of EGFR and inhibits receptor autophosphorylation induced by all known EGFR ligands. .
Gadoversetamide is a chelate containing gadolinium- which has paramagnetic properties andis responsible for the contrast enhancement effect in MRI- and the ligand versetamide.
Each SK has its own target ligand, and binding with the ligand is what starts the chain reaction that turn a gene on, off, up or down.
It is the ligand's structure which determines the number of interactions that can take place with the human androgen receptor ligand-binding domain.
Many different bonding modes(geometries) are recognized,but in most cases, the ligand is monodentate, attached to the metal through sulfur, which can be either planar and pyramidal η1.
Mangafodipir is a chelate containing the metal manganese- which has paramagnetic properties andis responsible for the contrast enhancement effect in MRI- and the ligand fodipir(dipyridoxyl diphosphate).
Engagement of PD-1 with the ligands PD-L1 and PD-L2, which are expressed in antigen presenting cells and may be expressed by tumours or other cells in the tumour microenvironment, results in inhibition of T-cell proliferation and cytokine secretion.
Data on stability, as well as in vitro and non-clinical studies,show that linear gadolinium agents release gadolinium from the ligand molecules to a greater extent than macrocyclic agents.
Two other genes have been associated with this condition: PDGFB and PDGFRB.[11] These genes are biochemically linked: PDGFBR encodes the platelet-derived growth factor receptor β andPDGFB encodes the ligand of PDGF-Rβ.
Necitumumab is a recombinant human IgG1 monoclonal antibody that binds with high affinity and specificity to the human epidermalgrowth factor receptor 1(EGFR) and blocks the ligand binding site, blocking activation by all known ligands and inhibiting relevant biological consequences in vitro.
Ligands in a complex dictate the reactivity of the central atom, including ligand substitution rates, the reactivity of the ligands themselves, and redox.
Data on stability, as well as in vitro and non-clinical studies,show that linear gadolinium-containing contrast agents(GdCAs) release gadolinium from the ligand molecules to a greater extent than macrocyclic agents.
A growing amount of data related to the molecular mechanisms of bone metabolism revealed new markers of bone turnover: proteins regulating osteoblasts' and osteoclasts' activation like the receptor activator of nuclear factor-kB(RANK) and its ligand(RANKL),and the natural inhibitor of the ligand-- the cytokine osteoprotegerin(OPG).
Secondly, competing for ligand reduces the activity of urease.
Effective ligand.
Remarkably, selenium has the ability to neutralize this ligand.
Ligand selection preparation.
Each hydroxocobalamin molecule can bind one cyanide ion by substituting the hydroxo ligand linked to the trivalent cobalt ion to form cyanocobalamin.
These NAAT include the PCR(polymerase chain reaction)and the LCR(ligand chain reaction).
Hanus and Devane when they found the natural ligand- anandamide- for the receptor(4).