Примери за използване на These transporters на Английски и техните преводи на Български
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These transporters are called lipoproteins.
The third moon is within range of these transporters.
These transporters are not typically used in the United States.
Co-administration with inhibitors of these transporters may increase the exposure to dalbavancin.
Therefore, caution is required when using medicinal products that interact with these transporters.
Хората също превеждат
Theoretically, induction of these transporters is also possible, and the net effect is presently unknown.
No clinically relevant interactions are expected to occur with these transporters, with the exception of BCRP.
Black cohosh can make these transporters less active and decrease how much of some medications get absorbed by the body.
Dasabuvir is not expected to affect medicinal products which are primarily excreted by the renal route via these transporters(see section 5.2).
Inhibition of these transporters is not expected to show clinically relevant increases in exposures of ombitasvir and dasabuvir.
No clinically relevant interactions are expected to occur with these transporters, with the administration of the parenteral formulation.
Overall, ertugliflozin is unlikely to affect the pharmacokinetics of concurrently administered medications that are substrates of these transporters.
Co-administration of Epclusa with medicinal products that are substrates of these transporters may increase the exposure of such medicinal products.
Therefore, clinical medicinal product interactions are unlikely to occur as a result of ponatinib-mediated inhibition of substrates for these transporters.
In vivo interactions of abemaciclib with clinically relevant substrates of these transporters, such as dofetilide or creatinine, may occur(see section 4.8).
Esketamine does not inhibit these transporters or multi-drug and toxin extrusion 1(MATE1) and MATE2-K, or organic cation transporter 2(OCT2), OAT1, or OAT3.
Increased plasma concentrations of co-administered medicinal products that are substrates of these transporters(e.g. metformin) cannot be excluded.
There is potential for inhibitors of these transporters to increase concentrations of boceprevir; the clinical implications of these interactions are not known.
Maraviroc is a substrate for the transporters P-glycoprotein and OATP1B1,but the effect of these transporters on the exposure to maraviroc is not known.
Medicinal products that are sensitive substrates of these transporters and for which elevated plasma levels are associated with serious events are contraindicated(see Table 2).
Therefore, interactions of ceftaroline with medicinal products that are substrates orinhibitors(e.g. probenecid) of these transporters would not be expected.
This may result in increased sytemic exposure of substrates of these transporters, such as dabigatran etexilate, ciclosporin, rosuvastatin and potentially digoxin.
Therefore, clinical drug-drug interactions as a result of ceritinib-mediated inhibition of substrates for these transporters are unlikely to occur.
Patients should be closely monitored when Alunbrig is coadministered with substrates of these transporters with a narrow therapeutic index(e.g., digoxin, dabigatran, methotrexate).
However, due to its high permeability and bioavailability,the risk of clinically relevant interactions with medicinal products that inhibit these transporters is unlikely.
Co-administration of cobicistat with medicinal products that are substrates of these transporters can result in increased plasma concentrations of the co-administered medicinal products.
In vitro studies show that cobimetinib is not a substrate of the liver uptake transporters OATP1B1, OATP1B3 and OCT1, however,it weakly inhibits these transporters.
Co-administration of Tybost in patients receiving medicinal products that are substrates of these transporters may result in increased plasma concentrations of the co-administered medicinal products.
Hence, clinically relevant drug-drug interactions are unlikely when apremilast is co-administered with drugs that are substrates or inhibitors of these transporters.
Velpatasvir is an inhibitor of drug transporter P-gp, BCRP, OATP1B1 and OATP1B3 andits involvement in drug interactions with these transporters is primarily limited to the process of absorption.