Примери за използване на Uridine на Английски и техните преводи на Български
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What Exactly Is Uridine?
Uridine is one of the major components.
The test stimulate the incorporation of uridine into thymocyte RNA.
Uridine also supports the health and function of liver mitochondria.
Febuxostat metabolism depends on Uridine Glucuronosyl Transferase(UGT) enzymes.
Sources of uridine: there are significant numbers of uridine in meat, fish and vegetable.
Glecaprevir and pibrentasvir are weak inhibitors of cytochrome P450(CYP)3A and uridine glucuronosyltransferase(UGT) 1A1 in vivo.
The tubers contain uridine, malic acid, neurotoxins, in a natural state.
In vitro data indicate that regorafenib is metabolized by cytochrome CYP3A4 and uridine diphosphate glucuronosyl transferase UGT1A9.
Also, emtricitabine did not inhibit uridine 5'-diphosphoglucuronyl transferase, the enzyme responsible for glucuronidation.
Etravirine is metabolised by CYP3A4, CYP2C9 andCYP2C19 followed by glucuronidation of the metabolites by uridine diphosphate glucuronosyl transferase(UDPGT).
Uridine is a type of nucleoside and along with adrenosine, guanine, and cytidine, is one of the four basic components of ribonucleic acid(RNA).
In vitro studies indicated that crizotinib is a weak inhibitor of uridine diphosphate glucuronosyltransferase(UGT)1A1 and UGT2B7.
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RNA was produced by a DNA-dependent RNA polymerase using nucleotides similar to those of DNA with the exception that thymidine in DNA was replaced by uridine in RNA.
Uridine diphosphoglucuronyl transferase UGT1A1 and UGT1A3 are responsible for glucuronidation, and bacteria in the lower gastrointestinal tract may be responsible for the cleavage pathway.
The RNA was produced by a DNA-dependent RNA polymerase using nucleotides similar to those of DNA,with the exception that the DNA nucleotide thymidine was replaced by uridine in RNA.
Elvitegravir may have the potential to induce CYP2C9 and/or inducible uridine diphosphate glucuronosyltransferase(UGT) enzymes; as such it may decrease the plasma concentration of substrates of these enzymes.
Medicinal products that affect etravirine exposure Etravirine is metabolised by CYP3A4, CYP2C9 andCYP2C19 followed by glucuronidation by uridine diphosphate glucuronosyl transferase(UDPGT).
Uridine is a nucleotide that acts as a precursor needed- in conjunction with the omega-3 fatty acid docosahexaenoic acid(DHA) and the B vitamin-like compound choline- for the synthesis of membrane phospholipids and brain synapses.
RNA is produced by a DNA-dependent RNA polymerase using nucleotides similar to those of DNA with the exception of Thymidine in DNA,replaced by Uridine in RNA.
The scientists looked for three nucleotides in breast milk(adenosine,guanosine and uridine), which excite or relax the central nervous system, promoting restfulness and sleep, and observed how these varied throughout a 24-hour period.
Loxapine is not expected to cause clinically important pharmacokinetic interactions with medicinal products that are either metabolised by cytochrome P450(CYP450) isozymes orglucuronidated by human uridine 5'-diphosphoglucuronosyl transferases(UGTs).
To reach the conclusion, scientists looked for three nucleotides in breast milk(adenosine,guanosine and uridine), which excite or relax the central nervous system, promoting restfulness and sleep, and observed how these varied throughout a 24-hour period.
Intracellular hydrolytic prodrug cleavage catalysed by enzymes including carboxylesterase 1 andsequential phosphorylation steps catalysed by nucleotide kinases result in formation of the pharmacologically active uridine nucleoside analogue triphosphate.
Sofosbuvir is a nucleotide prodrug that undergoes intracellular metabolism to form the pharmacologically active uridine analogue triphosphate(GS-461203), which can be incorporated into HCV RNA by the NS5B polymerase and acts as a chain terminator.
Following coadministration of dapagliflozin with rifampicin(an inducer of uridine 5'-diphosphoglucuronosyl transferase[UGT] and CYP3A4/5), a 22% decrease in dapagliflozin systemic exposure(AUC) was observed, but with no clinically meaningful effect on 24-hour urinary glucose excretion.
In particular, it has long been known that such components as nucleotides- adenosine,guanosine and uridine- have an exciting or depressing effect on the nervous system of the child, causing a healthy dream, or, conversely, anxiety.
Sofosbuvir is a nucleotide prodrug that undergoes intracellular metabolism to form the pharmacologically active uridine analogue triphosphate(GS-461203), which can be incorporated into HCV RNA by the NS5B polymerase and acts as a chain terminator.