Примери коришћења Second messenger на Енглеском и њихови преводи на Српски
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I do not know, bring them the second messenger.
The second messenger of verse 3:1 is the Lord Himself.
They can not get any on the two e-mail nor the second messenger.
DAG acts as a second messenger that activates protein kinase C(PKC) and IP3 helps in phosphorylation of some proteins.
G-protein signaling, coupled to cyclic nucleotide second messenger.
He found that epinephrine had to trigger a second messenger, cyclic AMP, for the liver to convert glycogen to glucose.
Gs in turn activates adenylate cyclase which increases intracellular levels of the second messenger cAMP.
These signals are then transmitted inside the cell by second messenger systems that often involved the phosphorylation of proteins.
Its activity is mediated by G proteins that activate several different second messenger systems.
Bh inositol important role as signaling substance("second messenger") in the body cell whole-wheat products Can be made by the body itself.
Autoreceptors are usually G protein-coupled receptors(rather than transmitter-gated ion channels)and act via a second messenger.[2].
Cyclic di-GMP(also called cyclic diguanylate and c-di-GMP)is a second messenger used in signal transduction in a wide variety of bacteria.
It acts as a"second messenger" in your cells, which means that it responds to chemical signals from outside your cells and then triggers a response inside your cell.
But nitric oxide acts on the blood vessels not independently,and through the activation of the second messenger called cGMP(cyclic guanosine monophosphate).
IP3 acts as a second messenger to dramatically increase ionic calcium inside the cytosol(via release from the endoplasmic reticulum or influx from the extracellular environment via ion channels).
The cyclic nucleotide phosphodiesterases comprise a group of enzymes that degrade the phosphodiester bond in the second messenger molecules cAMP and cGMP.
The ligands that bind to them are usually intracellular second messengers like inositol trisphosphate(IP3) and extracellular lipophilic hormones like steroid hormones.
Cyclic guanosine monophosphate(cGMP) is a cyclic nucleotide derived from guanosine triphosphate(GTP). cGMP acts as a second messenger much like cyclic AMP.
Both Gα-GTP and Gβγ can then activate different signaling cascades(or second messenger pathways) and effector proteins, while the receptor is able to activate the next G protein.
Additionally, metabotropic glutamate receptors may modulate synaptic plasticity by regulating postsynaptic protein synthesis through second messenger systems.
Greengard and his fellow researchers studied the behavior of second messenger cascades that transform the docking of a neurotransmitter with a receptor into permanent changes in the neuron.
Gαq/11 stimulates the membrane-bound phospholipase C beta,which then cleaves PIP2(a minor membrane phosphoinositol) into two second messengers, IP3 and diacylglycerol(DAG).
These receptors generally function via intracellular second messengers, including cyclic AMP(cAMP), cyclic GMP(cGMP), inositol 1,4,5-trisphosphate(IP3) and the calcium(Ca2+)-calmodulin system.
This is accomplished by direct stimulation of the membrane-associated enzyme adenylate cyclase.cAMP can then act as a second messenger that goes on to interact with and activate protein kinase A(PKA).
The D4 receptor is considered to be D2-like in which the activated receptor inhibits the enzyme adenylate cyclase,thereby reducing the intracellular concentration of the second messenger cyclic AMP.
Aside from the genetic material of the cell,nucleic acids often play a role as second messengers, as well as forming the base molecule for adenosine triphosphate(ATP), the primary energy-carrier molecule found in all living organisms.
In contrast, when a metabotropic receptor is activated, a series of intracellular events are triggered that can also result in ion channels opening or other intracellular events, butinvolve a range of second messenger chemicals.
However while Org 27569 increases the ability of CB1 agonists to bind to the receptor,it decreases their efficacy at stimulating second messenger signalling once bound, and so in practice behaves as an insurmountable antagonist of CB1 receptor function.
Traditional pharmacology posits that a ligand can be either classified as an agonist(full or partial), antagonist or more recently an inverse agonist through a specific receptor subtype, andthat this characteristic will be consistent with all effector(second messenger) systems coupled to that receptor.
Both of these fields are closely connected since both are concerned with the interactions of neurotransmitters, neuropeptides, neurohormones, neuromodulators,enzymes, second messengers, co-transporters, ion channels, and receptor proteins in the central and peripheral nervous systems.