The success of anticancer therapy is affected by the patient's nutrition status before and during treatment,which influences the patient's ability to tolerate therapy.
The European Union's Scientific Committee on Food did not set an Acceptable Daily Intake(ADI),but derived a Tolerable Upper Intake Level(UL) for vitamin E of 300 mg/day for adults.
The success of cáncer therapy is determined by the nutritional status of the patient before and during treatment,by affecting the patient's ability to tolerate the therapy.
There are also safety issues to be considered,such as potentials for tolerance, abuse, dependence, withdrawal(including risk of rebound insomnia), and drug-drug and drug-disease interactions.
In the absence of good data, a dose of 1 milligram per kilogram of body weight per day is where most patients start when using CBD for epilepsy-and this seems to be well tolerated.
Every vitamin has an RDA- or recommended dietary allowance(the recommended daily intake amount) and a UL-or upper tolerable limit(the maximum amount you can take before experiencing side effects).
It will be understood by those of ordinary skill in the art, however,that a patient may insist upon a lower dose or tolerable dose for medical reasons, psychological reasons or for virtually any other reason.
Although the Institute of Medicine did not establish a tolerable upper intake level(UL) for these omega-3 fatty acids, caution was advised with the use of supplemental EPA and DHA, especially in those who are at increased risk of excessive bleeding(see Drug interactions and Nutrient interactions)(1).
Early phase I/IItrials from Indiana University identified the maximum tolerated dose of three-fraction SBRT at 18 Gy× 3 for T1 tumors, and this regimen resulted in 2-year OS of 55% and 2-year local tumor control of 95%.
In some embodiments, the amount of the antimicrobial agent in the composition is below the level that induces a toxicological effect(i.e., above a clinically acceptable level of toxicity) or at a level where a potentialside effect can be controlled or tolerated when the composition is administered to an individual.
The theory behind international radiation exposureprotection standards has shifted from'tolerance dose standards', which recognize the existence of'safe doses', to permissible doses', which are considered acceptable radiation doses- but which do not rule the influence of radiation on genes- for the average human.
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