他莫昔芬 英语是什么意思 - 英语翻译

• tamoxifen

在 中文 中使用 他莫昔芬 的示例及其翻译为 英语

他莫昔芬-该药物减少体内雌激素的产生，从而增加睾酮的浓度（142％的初始水平）。
Tamoxifen- the drug reduces the production of estrogens in the body, thereby increasing the concentration of testosterone(142% of the initial level).

而他莫昔芬在乳腺癌治疗中的作用的初步结果显得那么乐观，进一步研究提出严重关切，它的广泛使用。
While the initial findings of Tamoxifen's role in breast cancer treatment seemed so promising, further research presented grave concerns for its widespread use.

他莫昔芬组的全因死亡率过高（分别为25例和11例；P=0.028），作者将其归因于偶然。
There was an excess of all-cause mortality in the tamoxifen group(25 vs. 11; P= .028), which the authors attributed to chance.

虽然有他莫昔芬和阿那曲唑-停止一些女性患乳腺癌的-这些药物有副作用毋庸置疑的好处。
And although there are undoubted benefits of tamoxifen and anastrozole- stopping some women from getting breast cancer- these drugs come with side effects.

一些女性也选择化学预防药物，如他莫昔芬，这可以降低风险，同时密切监测和改变生活方式.
You can also opt for chemopreventive drugs such as tamoxifen, which reduce risk, along with close monitoring and lifestyle changes.

他莫昔芬以20mg/d的剂量给药5年，对乳腺癌的治疗和预防有效，但毒性限制了其广泛使用。
Tamoxifen administered for 5 years at 20 mg/d is effective in breast cancer treatment and prevention, but toxicity has limited its broad use.

他莫昔芬柠檬酸盐是一种选择性雌激素受体调节剂（SERM），由ICI于1961年创建，现称为阿斯利康。
Tamoxifen Citrate is a selective estrogen receptor modulator(SERM), which was created in 1961 from ICI now known as AstraZenaca.

这些研究表明，一直在他莫昔芬的妇女做的经验，有统计上MBD的显着减少。
These studies have consistently demonstrated that women on tamoxifen do experience a statistically significant reduction in MBD.

他莫昔芬也被用来作为化学预防剂，以减少高风险的妇女患乳腺癌的风险。
Tamoxifen has also been used as a chemopreventive agent to reduce the risk of breast cancer in women at high risk.

两种药物的浸润性乳腺癌发病率大致相同，但是他莫昔芬组的非浸润性癌症较少。
Invasive breast cancer incidence was approximately the same for both drugs, but there were fewer noninvasive cancers in the tamoxifen group.

对于处于我这种风险水平的女性，服用激素治疗药物他莫昔芬五年可以降低75%的风险。
For women at my level of risk, taking the hormone therapy drug tamoxifen for five years can reduce that risk by 75%.

他莫昔芬20mg/天剂量通常被视为先进，辅助和预防设置的最佳剂量。
A 20 mg/day dose of tamoxifen is generally viewed as the optimal dose in the advanced, adjuvant, and prevention settings.

另外一项研究表明，仔细选择的70岁以上的患者在乳房肿瘤切除术后用他莫昔芬治疗时，放疗没有额外的生存获益。
An additional study demonstrated that carefully selected patients aged 70 and older had no additional survival benefit with radiation therapy when treated with tamoxifen after lumpectomy.

他莫昔芬和雷洛昔芬的研究（STAR）（NSABPP-2）比较了他莫昔芬和雷洛昔芬在19,747名平均监测时间为3.9年的高危女性中的作用。
The Study of Tamoxifen and Raloxifene(STAR)(NSABP P-2) compared tamoxifen and raloxifene in 19,747 high-risk women who were monitored for a mean of 3.9 years.

他莫昔芬帮助许多女性罹患乳腺癌并延长生命。
Tamoxifen has helped many women beat breast cancer and extend their lives.

总增加妇女谁使用他莫昔芬在所有的风险是50％。
The total increased risk for all women who used tamoxifen at all was 50%.

他莫昔芬：用于预防某些乳腺癌。
Abemaciclib: Used for certain types of breast cancer.

一般来说，他莫昔芬在三个不同的背景下实施有三个主要原因：.
Generally speaking, Tamoxifen is implemented for three main reasons, in three different contexts:.

为了避免这种情况，他莫昔芬应与AI（芳香酶抑制剂）一起使用。
In order to avoid this, Tamoxifen should be used alongside an AI(aromatase inhibitor).

他莫昔芬是作为化学预防妇女乳腺癌高风险的代理批准的第一个药物。
Tamoxifen is the first drug approved as chemoprevention agent for women at high-risk for breast cancer.

他莫昔芬是乳腺癌的药物，已经使用了几十年来治疗疾病和阻止它回来。
Tamoxifen is a breast cancer drug that has been available for decades to treat the disease and stop it coming back.

L他莫昔芬（Nolvadex，Tamofen）用于绝经前和绝经后妇女。
Tamoxifen(Nolvadex, Tamofen) is given to premenopausal and post-menopausal women.

使用的动物模型与40多年前用于发现他莫昔芬可以预防乳腺癌的模型相同。
The animal model used is the same that was used over 40 years ago to discover that tamoxifen prevents breast cancer.

抑郁症已报道％的女性30他莫昔芬作为一个潜在的副作用。
Depression has reported as a potential side-effect of tamoxifen in 30% of women.

他莫昔芬使用应仅限于5年的时间，因为受益超出这个时间还没有记载。
Tamoxifen use should be limited to 5 years' duration because a benefit beyond this time has not been documented.

他们发现当他莫昔芬靶向癌细胞时，他们有时会通过提高AKT基因的表达来应对。
They discovered that when Tamoxifen targeted cancer cells, they sometimes responded by elevating expression of a gene known as AKT.

他莫昔芬的持续使用时间可以延长到10年，新的数据显示还有额外的获益。
Tamoxifen use may be extended to 10 years based on new data demonstrating additional benefit.

他们发现当他莫昔芬靶向癌细胞时，他们有时会通过提高AKT基因的表达来应对。
They discovered that when cancer cells are fed tamoxifen, they sometimes respond by elevating expression of a gene known as AKT.

然而，如果给他们喂他们他莫昔芬，同时，有可能大大减少细胞增殖的能力。
However, if one were to feed them Tamoxifen, at the same time, it was possible to dramatically curtail the cell's ability to proliferate.