Ví dụ về việc sử dụng Chloral hydrate trong Tiếng anh và bản dịch của chúng sang Tiếng việt
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Chloral hydrate was routinely administered in gram quantities.
If we find any traces of chloral hydrate, we will take the next step.".
Chloral hydrate is a starting point for the synthesis of other organic compounds.
Because of its status as a regulated substance, chloral hydrate can be difficult to obtain.
Chloral hydrate is produced from chlorine and ethanol in acidic solution.
S in the late 19th and early 20th centuries,until they were gradually superseded by chloral hydrate.
However, chloral hydrate was quite polar but nonetheless a potent hypnotic.
Ventricular fibrillation can be caused when this product isused in combination with general anesthetics such as chloral hydrate.
Chloral hydrate is soluble in both water and ethanol, readily forming concentrated solutions.
Increased urine glucose may be seen with medications,such as estrogens and chloral hydrate, and with some forms of kidney disease.
Chloral hydrate was also a significant object of study in various early pharmacological experiments.
In basic conditions the haloform reaction takes place and chloral hydrate is decomposed by hydrolysis to form chloroform.[21].
Finally, chloral hydrate was also the first hypnotic to be used intravenously as a general anesthetic.
It means that Dr. Mallory could claim he made a mistake,that he didn't know what effect chloral hydrate would have on a patient with porphyria.
In the United States, chloral hydrate is a schedule IV controlled substance and requires a physician's prescription.
Physically, he was in poor shape, relying upon morphine shots to deal with pain from back surgery andusing chloral hydrate, a sedative, to help him sleep.
Thus, chloral hydrate remained one of the major and persistent exceptions to this breakthrough discovery in pharmacology.
In 1875, Claude Bernard tried to determine if chloral hydrate exerted its action through a metabolic conversion to chloroform.
Chloral hydrate is used for the short-term treatment of insomnia and as a sedative before minor medical or dental treatment.
Dichloralphenazone is a prodrug of two pharmacologically distinct agents:the sedative agent, chloral hydrate, as well as antipyrine, a non-steroidal anti-inflammatory drug that works to decrease inflammation.
Chloral hydrate is metabolized in vivo to trichloroethanol, which is responsible for its physiological and psychological effects.[22].
Potassium bromide and sodium bromide were used as anticonvulsants and sedatives in the late 19th and early 20th centuries,until they were gradually superseded by chloral hydrate and then the barbiturates.
GABAergic pro-drugs include chloral hydrate, which is metabolised to trichloroethanol[70], which then acts via the GABAA receptor.
Chloral hydrate is an ingredient used to make Melzer's reagent, an aqueous solution that is used to identify certain species of fungi.
Friedrich Nietzsche(1844- 1900) regularly used chloral hydrate in the years leading up to his nervous breakdown, according to Lou Salome and other associates.
Chloral hydrate had some other important advantages that kept it in use for five decades despite the existence of more advanced barbiturates.
In this synthesis, chloral hydrate reacts with aniline and hydroxylamine to give a condensation product which cyclicizes in sulfuric acid to give the target compound:[17].
While chloral hydrate was converted to a different metabolite than chloroform, it was found that was converted into the more lipophilic molecule 2,2,2-Trichloroethanol.
The metabolite of chloral hydrate exerts its pharmacological properties via enhancing the GABA receptor complex[23] and therefore is similar in action to benzodiazepines, nonbenzodiazepines and barbiturates.
Reaction with chloral hydrate in the presence of potassium bisulfate yields the lactone of tetra-oxydiphenyl methane carboxylic acid.[10] In alcoholic solution it condenses with sodium acetoacetate to form 4-methylumbelliferone.[11].