Ví dụ về việc sử dụng Clinical effect trong Tiếng anh và bản dịch của chúng sang Tiếng việt
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The main clinical effect of liniment is based on the induction of early alpha interferon.
Gradually(once every 3 days)it is increased by 150-250 mg to achieve a clinical effect.
The first clinical effect appears after 2-4 days, the maximum- develops within 14 days.
Subsequent dosage(40-120 mg daily) should be based on the clinical effect obtained during the first weeks of therapy.
The clinical effect and/ or content of these substances in the blood plasma should be monitored;
After 24 hours, the dose may betitrated by 10%-20% increments every day until the desired clinical effect is achieved.
If there is no clinical effect after 4 weeks of therapy, the further use of Minirin is not appropriate;
Combining nebivolol with nicardipine slightly increased the plasma levels of both drugs,without changing the clinical effect.
The clinical effect was often excellent, but 5 years later it was found to cause retroperitoneal fibrosis after chronic intake.
Co-administration of nebivolol with cimetidine increased the plasma levels of nebivolol,without changing the clinical effect.
The clinical effect can be achieved more quickly by taking Madopar GSS“125” with Madopar“125” capsules or dispersible tablets.
The major product at the end of the metabolic pathway is circulating dapoxetine N-oxide,which is a weak SSRI and contributes no clinical effect.
If after a sufficiently long treatment the clinical effect cannot be achieved, Cortef is canceled and alternative therapy is prescribed.
The analogues of Vesticap capsules according to the active substance and the pharmacological, clinical effect are Vestibo, Betagis, Betagistin, Betanorm.
After the desired clinical effect is obtained, the maintenance dose should be reduced to the smallest amount necessary to control the symptoms.
In some cases, it is necessary to take a third dose, sometimes a single dose of300-400 mg is sufficient to achieve a clinical effect.
And only with insufficient clinical effect, but provided that the drug is well tolerated in this category of patients, the dose can be increased to 10 mg.
The initial daily dose for children weighing more than 25 kg- 5-15 mg/ kg(300 mg), gradually(5-10 mg/ kg per week),it is increased to achieve a clinical effect.
The dose should be increased gradually,when the optimum clinical effect is reached, a lowering of the dose begins until the minimum effective dose is reached.
Usually, the effective daily dose from the fourth day of treatment is 300-450 mg, however,depending on the tolerance and clinical effect, it can vary in the range of 150-750 mg.
The overall clinical effect of elevated mood and decreased anxiety is thought to be due to adaptive changes in neuronal function, resulting in enhanced serotonergic neurotransmission.
This is because the large store of pre-formed T3 and T4 in the thyroid gland and bound to thyroid binding globulin(99% bound)has to be depleted before any beneficial clinical effect occurs.
If no clinical effect is observed after two weeks of drug therapy, the dosage is increased to 50 mg per day(after careful evaluation of the benefit-risk ratio for the patient and under strict medical supervision of the liver function).
If the effect of the application is not enough, then you can increase the dose to 2 injections per day,but after the development of a full-fledged clinical effect, they again switch to a single use of the drug.
The goal of this therapy is to achieve a maximum clinical effect in a patient taking the drug for a long time and to minimize certain side effects, such as stunting in children, Cushing's syndrome, suppression of the pituitary-adrenal system and withdrawal syndrome.
In ex vivo models of arthritis, IL-12/IL-23p40 was specifically identified as a downstream target of apremilast.[14]The importance of these individual factors for the clinical effect of apremilast is not clear.[3].
Strengthening the metabolism of estrogen and progestin can drugs with the content of Hypericum perforatum(Hypericum perforatum),because of which it is possible to reduce their clinical effect and change the profile of uterine bleeding.
This use of biomimicry, or the practice of using polymers that occur naturally in biology, provides a coating,with minimal thrombus deposition and no adverse clinical effect on late healing of the arterial vessel wall.