Ví dụ về việc sử dụng Griseofulvin trong Tiếng anh và bản dịch của chúng sang Tiếng việt
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Inside for 2-3 weeks: Griseofulvin.
Griseofulvin may cause severe toxicity.
Known side effects of griseofulvin include.
Griseofulvin has an elimination half life of 9 to 24 hours.
International Non-proprietary Name: Griseofulvin.
Griseofulvin should not be used during breastfeeding.
Known side effects of griseofulvin include.
Griseofulvin- a drug used in the treatment of fungal infections.
It is not known whether griseofulvin is excreted into human milk.
What drugs and substances can not be taken with griseofulvin.
Monitor serum levels of griseofulvin and the dose is increased if it is required.
Griseofulvin is used inside, after food, for one or several receptions.
Major metabolite 6- demethyl griseofulvin has no effect on microorganisms.
Griseofulvin may increase the effects of alcohol, patients should be alerted to this interaction.
The two main ones to watch out for are griseofulvin(Gris-PEG) and ketoconazole(Extina, Nizoral, Xolegel).
For example, women of childbearing age should not become pregnant during(and for one month after)treatment with griseofulvin.
Hypersensitivity to griseofulvin may occur, as a result of which it is necessary to refuse to take the drug.
The limit of the drug concentration in the blood is fixed 4-5 hours after administration,the maximum saturation of griseofulvin in plasma is 0.5-5 mg/ l.
They are prescribed griseofulvin in the infant dose, and if the child is breastfed, the mother takes the drug.
A similar reaction is presumably possible with the simultaneous use of preparations of Hypericum perforatum,topiramate, griseofulvin, oxcarbazepine, felbamate.
Griseofulvin(Grisovin): The side effects, which usually go away fairly quickly, may include headache, indigestion, and nausea.
It is recommended to use non-hormonal methods of contraception, as griseofulvin adversely affects the reproductive performance of both men and women;
Griseofulvin undergoes hepatic metabolism, mainly through oxidative demethylation by P450 enzyme and conjugation with glucuronic acid.
A similar property was found in rifampicin, carbamazepine, primidone, barbiturates and hydantoins, it is assumed in felbamate,topiramate, griseofulvin and oxcarbazepine.
It is not recommended to use griseofulvin in mild forms of the disease, when it is possible to confine with antifungal agents for external use.
Griseofulvin has been shown to be teratogenic in pregnant animals and there are case reports of human fetal abnormalities associated with griseofulvin.
Today, due to this species' high susceptibility to the antifungal drug griseofulvin, it has been eliminated from most parts of the world except rural central Asia and scattered rural areas of Africa.
Griseofulvin can cause headaches, fatigue, drowsiness, dizziness, and impaired co-ordination, which influence the ability to drive and use machines. If affected, patients should not perform activities that require alertness.
Phenobarbital, which is part of Valelerdine,reduces the antifungal activity of griseofulvin due to deterioration of absorption, the antibacterial effect of sulfonamides and antibiotics, doxycycline, estrogens and other drugs that are metabolized in the liver by way of oxidation, by accelerating their destruction.
Griseofulvin is indicated for the treatment of dermatophyte infections of the skin, hair, or nails which do not respond to topical treatment including tinea corporis, tinea pedis, tinea cruris, tinea barbae, tinea capitis, tinea unguium caused by susceptible strains of Trichophyton sp., Microsporum sp., or Epidermophyton sp….