Ví dụ về việc sử dụng Midazolam trong Tiếng anh và bản dịch của chúng sang Tiếng việt
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Increases midazolam concentration.
They know about the use of midazolam.
Midazolam is best avoided if at all possible in the first trimester and probably throughout pregnancy.
A sedative such as midazolam(Versed);
Midazolam can cause birth defects in an unborn baby, and generally should not be used during pregnancy.
Simultaneous use with midazolam, colchicum.
Midazolam is given only by or under the immediate supervision of a doctor trained to use this medicine.
Many drugs can interact with midazolam.
Midazolam is used to sedate a person who is having a minor surgery, dental work, or other medical procedure.
Dormicum solution is released for intramuscular injection, in 1 ml of which contains 5 or15 mg of the active ingredient- midazolam.
Multiple dosing of dapoxetine(60 mg/day for 6 days)decreased the AUCinf of midazolam(8 mg single dose) by approximately 20%(range- 60 to +18%).
Midazolam should be used only in a hospital, dentist office, or other clinic setting where any serious side effects can be quickly treated.
Multiple dosing of dapoxetine(60 mg/day for 6 days)decreased the AUCinf of midazolam(8 mg single dose) by approximately 20%(range- 60 to +18%).
Preparations with active substances, for the metabolism of which the participation of CYP3A4 enzymes is necessary(for example,Pimozide, Midazolam, Tsizaprid, etc.).
The drug inhibits P450 and enhances the effects of terfenadine, astemizole,indinavir, midazolam, calcium channel blockers, warfarin, cisapride and ciclosporin.
It is dangerous combination with midazolam, because this leads to a significant increase in the concentration of midazolam in the blood and the risk of developing psychomotor reactions.
Ramelteon has been evaluated for potential drug interactions with the following medications and showed no significant effects: omeprazole, theophylline,dextromethorphan, and midazolam, digoxin and warfarin.
You should not take midazolam if you have narrow-angle glaucoma, if you are allergic to cherries, or if you are allergic to midazolam or similar medicines(Valium, Xanax, Ativan, and others).
If second therapy fails to stop the seizures, treatment considerations should include repeating second-line therapy oranesthetic doses of either thiopental, midazolam, pentobarbital, or propofol(all with continuous EEG monitoring).
In seriously ill neonates, however,the terminal elimination half-life of midazolam is substantially prolonged(6.5 to 12.0 hours) and the clearance reduced(0.07 to 0.12 L/hr/kg) compared to healthy adults or other groups of pediatric patients.
It should not be administered with a wide range of drugs, including amprenavir, fosamprenavir, simvastatin, lovastatin, rifampin, rifabutin, rifapentine, St John's wort,astemizole, midazolam, triazolam, ergot medications, and several medications for acid reflux.[1].
Remimazolam was found to be both faster acting andshorter lasting than midazolam, and human clinical trials showed a faster recovery time and predictable, consistent pharmacokinetics, suggesting some advantages over existing drugs for these applications.[2][3].
Although clinical studies using antipyrine as a marker of cytochrome P450(CYP) activity showed no evidence of a drug interaction potential with Casodex,mean midazolam exposure(AUC) was increased by up to 80%, after co-administration of Casodex for 28 days.
A phase IIa trial comparing remimazolam to midazolam for upper endoscopy was published in December 2014, finding a similar safety profile.[7] Remimazolam was originally discovered in the late 1990s at Glaxo Wellcome in their labs in Research Triangle Park, NC.
Initial therapy phase(5-20 minutes of seizure activity) when it is clear the seizure requires medical intervention,a benzodiazepine(specifically IM midazolam, IV lorazepam, or IV diazepam) is recommended as the initial therapy of choice, given its demonstrated efficacy, safety, and tolerability.
Treatment initially includesmedications to sedate the person such as ketamine or midazolam and haloperidol injected into a muscle.[2] Rapid cooling may be required in those with high body temperature.[2] Other supportive measures such as intravenous fluids and sodium bicarbonate may be useful.[1] The risk of death among those affected is less than 10%.[1] If death occurs it is typically sudden and cardiac in nature.
Ro48-8684 is a water-soluble benzodiazepine derivative developed by Hoffman-LaRoche in the 1990s,which was designed along with Ro48-6791 as an improved replacement for midazolam, but ultimately proved to have little advantages over the parent drug and has not been introduced into clinical practice.[1][2].
Midazolam first came into use in 1976.[9] It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system.[10] Midazolam is available as a generic medication and is not very expensive.[7] The wholesale cost in the developing world of a vial is about 0.35 USD.[11] In many countries, it is a controlled substance.[3].
It is recommended that use be made of a hypnotic dose of a short acting barbiturate or another product such as propofol,etomidate, or midazolam in order to avoid coughing or laryngospasms, which can arise if induction is carried out with AErrane alone or in combination with oxygen or with an oxygen-nitrous oxide mixture.