severe anaphylaxis severe anemia severe angina severe anxiety severe aplastic anaemia severe arrhythmias severe arthritis severe asthma severe athletes severe attack severe back pain severe bacterial infection severe beating severe birth defects severe bleeding severe bleeds severe blistering severe blow severe bradycardia severe brain damage severe brain injury severe brain severe breathing difficulties severe breathing problems severe breathing severe breathlessness severe bronchospasm severe bruising severe budget severe burning severe burns severe cases can severe cases severe case severe casualties severe challenges severe changes severe chastisement severe chemical severe chest pain severe chronic neutropenia severe chronic pain severe chronic severe climate severe clinical signs severe clinical severe cold severe combined severe competition severe complications severe concussion severe conditions severe conflict severe confusion severe congenital severe consequences severe constipation severe constraints severe contamination severe contraction severe convulsions severe corrosion severe coughing severe course severe cramps severe crime severe crisis severe criticism severe critic severe cuts severe damage severe danger severe decline severe decrease severe defeat severe deficiency severe deformation severe degree severe dehydration severe delays severe dementia severe depression severe destruction severe deterioration severe diabetes severe diarrhea severe diarrhoea severe difficulties severe difficulty in breathing severe disabilities severe disability severe discoloration severe discomfort severe discrimination severe diseases severe disease severe disorders severe disruption severe distortions severe dizziness severe downturn severe drop severe drought severe drowsiness severe dyskinesia severe earthquake severe economic consequences severe economic crisis severe economic difficulties severe economic downturn severe economic problems severe economic recession severe economic severe eczema severe effects severe environmental damage severe environmental problems severe environments severe epilepsy severe erosion severe events severe exacerbations severe exercises severe eye severe fall severe famine severe fatigue severe fever severe fighting severe financial crisis severe financial difficulties severe financial problems severe financial severe fire severe flooding severe floods severe fluid retention severe flu severe form of the disease severe forms severe form severe frostbite severe frosts severe frost severe gains severe gastroenteritis severe gastrointestinal severe haemophilia severe haemorrhage severe hair loss severe handicap severe hardship severe harm severe head injury severe head trauma severe headaches severe headache severe health problems severe health severe hearing loss severe heart disease severe heart failure severe heartburn severe heart severe hemorrhage severe hemorrhaging severe hepatic disease severe hepatic dysfunction severe hepatic impairment severe hepatic insufficiency severe hepatic severe high blood pressure severe human rights violations severe humanitarian crisis severe hunger severe hyperglycaemia severe hypersensitivity severe hypertension severe hypoglycaemia severe hypotension severe hypothermia severe illness severe imbalances severe immunosuppression severe impact severe impairment severe implications severe incontinence severe infection with a high temperature severe infections in children severe infections severe infection severe inflammation severe influence severe injuries severe injury severe insomnia severe internal bleeding severe internal injuries severe internal