substantial renovation substantial report substantial requirements substantial research substantial reserves substantial resources substantial response substantial responsibility substantial restrictions substantial restructuring substantial results substantial revenue substantial review substantial revision substantial reward substantial rise substantial risk substantial role substantial savings substantial saving substantial scale substantial scope substantial section substantial settlement substantial share substantial shift substantial shortcomings substantial simplification substantial size substantial snack substantial source substantial step substantial strengthening substantial study substantial subsidies substantial success substantial sum of money substantial sums substantial sum substantial support substantial surplus substantial synergies substantial tax substantial technical assistance substantial threat substantial time substantial trade substantial transfer substantial transformation substantial uncertainty substantial use substantial value substantial variations substantial variation substantial variety substantial volume substantial way substantial weakening substantial wealth substantial weight-loss substantial weight substantial work substantial worrying substantiality substantially accelerated substantially affect substantially altered substantially amended substantially boosts substantially changed substantially completed substantially different substantially enhances substantially enlarged substantially expanded substantially extended substantially greater substantially higher substantially improved substantially improves substantially improve substantially increasing substantially interested substantially larger substantially lessen substantially less substantially limited substantially lowered substantially lower substantially modified substantially raises substantially reduced substantially reduces substantially reduce substantially reducing substantially reinforced substantially restrict substantially revised substantially similar substantially simplified substantially smaller substantially strengthened substantially weakened substantially substantial to substantiate the application to substantiate the claim substantiated complaints substantiated information substantiated reports substantiated request substantiated substantiates substantiate substantiating substantiation substantive action substantive amendments substantive amendment substantive arguments substantive aspects substantive assessment substantive basis substantive changes substantive change substantive conditions substantive content substantive criminal law substantive criteria substantive debate substantive decisions substantive differences substantive discussion substantive elements substantive evidence substantive examination substantive expertise substantive findings substantive impact substantive improvements substantive issues substantive knowledge substantive law substantive matters substantive measures substantive meeting substantive negotiations substantive obligations substantive part substantive policy substantive preparation substantive principles substantive problems substantive process substantive progress substantive proposals substantive provisions substantive questions substantive reasons substantive reform substantive regulation substantive requirements substantive results substantive revision substantive rights substantive rules substantive scope substantive standards substantive steps substantive talks substantive test substantive work substantively substantive substation automation substation design substations substation substeps substituents substituent substitutability substitutable substitute for a varied diet substitute for experience substitute for insulin substitute for sugar substitute fuels substitute materials substitute members substitute member substitute products substitute teacher substituted substitutes all other symbols substitutes all symbols substitutes for all symbols substitutes for any other symbol substitutes substitute