Total clearance is around 2 l/ h, and less than 5% of the dose is excreted in the urine.
Total' clearance' er cirka 2 L/ h og mindre end 5% af dosis udskilles i urinen.
About 70% of the dose is excreted in the urine as inactive metabolites.
Af dosis udskilles i urinen som inaktive metabolitter.
One-eighth of the follitropin alfa dose is excreted in the urine.
En ottendedel af follitropin alfa- dosis udskilles i urinen.
Less than 1% of the dose is excreted as unchanged active ingredient.
Mindre end 1% af dosen udskilles som uændret aktivt stof.
Valsartan does not undergo extensive biotransformation and 70% of the available dose is excreted.
Valsartan undergår ikke nogen omfattende biotransformation, og 70% af den tilgængelige dosis udskilles.
About 90% of all the dose is excreted within one day.
Omkring 90% af al den dosis udskilles inden for en dag.
Less than 2% of the dose is excreted in the urine as unchanged irbesartan.
Mindre end 2% af dosis udskilles uomdannet i urinen som irbesartan.
After multiple dosing, less than 3% of the lopinavir dose is excreted unchanged in the urine.
Efter flergangsdosering bliver mindre end 3% af lopinavir dosis udskilt uændret i urinen.
Approximately 20% of a timolol dose is excreted in the urine unchanged and the remainder excreted in urine as metabolites.
Cirka 20% af en dosis timolol udskilles uændret via urinen, og resten udskilles i urinen som metabolitter.
One- eighth of the GONAL-f dose is excreted in the urine.
En ottendedel af en GONAL- f- dosis udskilles i urinen.
Metabolism 95% of the dose is excreted in the urine as drug and metabolites.
Metabolisme 95% af dosis udskilles i urinen som lacosamid og metabolitter.
After intravenous administration, 42±7% of dose is excreted unchanged in the urine.
Efter i. v. administration udskilles 42±7% af dosis uændret i urinen.
About 3% of the administered dose is excreted in urine as unchanged drug.
Af den indgivne dosis udskilles uændret i urinen.
Most(about 87%) of the administered dose is excreted in the urine as MPAG.
Af den administrerede dosis udskilles i urinen som MPAG.
Approximately 38% of an intravenous dose is excreted in the urine as unchanged substance.
Af en intravenøs dosis udskilles uomdannet med urinen.
Approximately 15% of the administered TRISENOX dose is excreted in the urine as unchanged AsIII.
Cirka 15% af den indgivne TRISENOX- dosis udskilles i urinen som uændret AsIII.
Also, less than 0.1% of the administered dose is excreted as the metabolite N-desethyloxybutynin.
Desuden udskilles mindre end 0, 1% af den indgivne dosis som metabolitten N- desethyloxybutynin.
Approximately 30% of the administered dose is excreted into the urine over 48 hours with 1% as unchanged busulfan.
Omtrent 30% af den indgivne dosis udskilles med urinen i løbet af 48 timer med 1% som uomdannet busulfan.
Approximately 70% of the administered human dose is excreted in the urine, mainly as conjugates of gemfibrozil and its metabolites.
Omtrent 70% af den humane dosis udskilles i urinen, hovedsagelig som konjugater af gemfibrozil og dets metabolitter.
After administration of toltrazuril to the target animal the dose is excreted as a mixture of parent compound and a major metabolite toltrazuril sulfone.
Efter indgivelse af toltrazuril til måldyret udskilles dosis som en blanding af moderstoffet og hovedmetabolitten, toltrazurilsulfon.
Excretion In healthy men, approximately 20-30% of a single intravenously administered dose is excreted in the urine, suggesting that 70-80% is excreted via the hepato-biliary system.
Af en enkelt intravenøst administreret dosis udskilt i urinen, hvilket tyder på, at 70- 80% udskilles via lever- galde systemet.
Following single intravenous injection of synthetic human I-calcitonin, 95% of the dose is excreted in the 48-hour urine; 2.4% of the dose is accounted for by unchanged I-calcitonin and the rest by iodinated degradation products.
Efter enkelt intravenøs injektion af syntetisk humant I- calcitonin, udskilles 95% af dosis i 48- timers urinen; 2, 4% af dosis udskilles som uændret I- calcitonin og resten som iodide nedbrydningsprodukter.
About two third of the dose are excreted unchanged in urine.
Omkring to tredjedele af dosis udskilles uomdannet i urinen.
The majority of the dose was excreted within 96 hours.
Størstedelen af dosis blev udskilt inden for 96 timer.
A mass balance study demonstrated that> 90% of the dose was excreted within 24 hours.
Et massebalancestudie viste at> 90% af dosis blev udskilt inden 24 timer.
Excretion After intravenous administration, 25% of the dose was excreted as metabolites within 24 hours.
Udskillelse Efter intravenøs administration blev 25% af dosis udskilt som metabolitter inden for 24 timer.
Of the dose was excreted in urine, of which at least 95% could be attributed to unchanged sugammadex.
Af dosis blev udskilt i urinen, hvor 95% var uomdannet sugammadex.
Less than 1% of the administered radioactive dose was excreted in the urine, indicating negligible renal clearance.
Mindre end 1% af den indgivne radioaktive dosis blev udskilt i urinen, hvilket tyder på en ubetydelig renal clearance.
The major route of excretion was via urine, accounting for a mean 95% of the dose approximately 93% of the dose was excreted within 48 hours.
Hovedparten blev udskilt via urinen, gennemsnitligt 95% af dosis ca. 93% af dosis var udskilt inden for 48 timer.
Resultater: 76,
Tid: 0.0419
Hvordan man bruger "dose is excreted" i en Engelsk sætning
Less than 2% of administered dose is excreted through the biliary system .
Approximately 10% of a dose is excreted in the urine as unchanged drug.
About 11% of the dose is excreted in the urine as metabolites [Label].
Ten to 30% of the administered dose is excreted unchanged in the urine.
Between 0.004% and 0.019% of the total administered dose is excreted into milk.
Elimination: 62% of the dose is excreted in the urine in 24 h.
Generally, most (99%) of a single dose is excreted within 4 days .
Hvordan man bruger "dosis udskilles" i en Dansk sætning
Plasmahalveringstid ca. 8 timer, men betydelig interindividuel variation forekommer.
60-65% af den indgivne dosis udskilles i urinen og 25-30% med fæces.
Mindre end 2 % af den oralt administrerede dosis udskilles som moderstoffet.
Det omdannes fortrinsvis til inaktive metabolitter, og ca. 50 % af dosis
udskilles gennem urinen.
Ca. 38 % af en intravenøs dosis udskilles uomdannet med urinen.
Ca. 90 % af rosuvastatin dosis udskilles uomdannet i fæces (bestående af absorberet og
uabsorberet stof) og den resterende del i urinen.
Ca. 20 % af den indgivne dosis udskilles i urinen som glucuronidester.
Ca. 35% af dosis udskilles som metabolitter gennem nyrerne.
Ca. 60 % af den
perorale dosis udskilles uforandret i løbet af 48 timer.
Elimination: Erlotinib udskilles hovedsageligt som metabolitter via fæces (>90 %), og kun en mindre del (ca. 9 %) af en oral dosis udskilles renalt.
Ca. 95% af den absorberede dosis udskilles uomdannet i urinen.
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