Eksempler på brug af Hydroxocobalamin på Engelsk og deres oversættelser til Dansk
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Hydroxocobalamin may be given to a pregnant woman.
It contains the active substance hydroxocobalamin vitamin B12a.
Det indeholder det aktive stof hydroxocobalamin vitamin B12a.Hydroxocobalamin will lower blood cyanide concentrations.
Hydroxocobalamin reducerer cyanidkoncentrationen i blodet.Cyanokit 2.5 g powder for solution for infusion Hydroxocobalamin.
Cyanokit 2, 5 g pulver til infusionsvæske, opløsning Hydroxocobalamin.Hydroxocobalamin may interfere with all urine colorimetric parameters.
Hydroxocobalamin kan interferere med alle kolorimetriske urinprøver.Observed in vitro interferences of hydroxocobalamin with laboratory tests.
Observeret in vitro- interferens af hydroxocobalamin med laboratorieprøver.Hydroxocobalamin has not been evaluated for carcinogenic potential.
Hydroxocobalamin er ikke blevet vurderet med henblik på kræftfremkaldende potentiale.The active substance in Cyanokit, hydroxocobalamin, reacts with cyanide in the body.
Det aktive stof i Cyanokit, hydroxocobalamin, reagerer med cyanid i kroppen.Increase in blood pressure may occur in patients receiving hydroxocobalamin.
Det kan forekomme, at blodtrykket stiger hos de patienter, der får hydroxocobalamin.Hydroxocobalamin(vitamin B12a) has been used as a vitamin supplement since the 1950s.
Hydroxocobalamin(vitamin B12a) har været anvendt som vitamintilskud siden 1950' erne.Tell your doctor or other health personnel• if you are allergic to hydroxocobalamin or vitamin B12.
Fortæl det til lægen eller plejepersonalet• hvis du er allergisk over for hydroxocobalamin eller B12- vitamin.They are called hydroxocobalamin, adenosylcobalamin, methylcobalamin, and cyanocobalamin.
De hedder hydroxocobalamin, adenosylcobalamin, methylcobalamin og cyanocobalamin.In particular, liver fibrosis was observed in dogs after administration of hydroxocobalamin for 4 weeks at 300 mg/ kg.
Specielt blev der observeret leverfibrose hos hunde efter administration af 300 mg/ kg hydroxocobalamin i 4 uger.In general, the effectiveness of hydroxocobalamin in paediatric patients was similar to that of adults.
Generelt var virkningen af hydroxocobalamin blandt pædiatriske patienter sammenlignelig med den hos voksne.Consequently, these medicinal products must not be administered simultaneously through the same intravenous line as hydroxocobalamin.
Disse lægemidler må derfor ikke administreres samtidig med hydroxocobalamin gennem den samme intravenøse adgang.In general, the effectiveness of hydroxocobalamin in these patients was similar to that of younger patients.
Blandt disse patienter var effektiviteten af hydroxocobalamin generelt sammenlignelig med den hos yngre patienter.Haemodialysis may be effective in such a circumstance, butis only indicated in the event of significant hydroxocobalamin- related toxicity.
Hæmodialyse kan være effektivt i denne situation, mener kun indiceret i tilfælde af en signifikant hydroxocobalamin- relateret toksicitet.Because hydroxocobalamin will be administered in potentially life-threatening situations, breast- feeding is not a contraindication to its use.
Da hydroxocobalamin administreres i potentielt livstruende situationer, er amning ikke en kontraindikation.Dogs then received sodium chloride 9 mg/ ml, 75 mg/ kg or150 mg/ kg hydroxocobalamin, administered intravenously over 7.5 minutes.
Derefter fik hundene natriumklorid 9 mg/ ml, 75 mg/ kg eller150 mg/ kg hydroxocobalamin, der blev administreret intravenøst i 7, 5 min.Because of its deep red colour, hydroxocobalamin has the potential to induce a red colouration of the skin and therefore may interfere with burn assessment.
Da hydroxocobalamin er mørkerødt, kan det føre til en rødfarvning af huden og kan derfor interferere med vurderingen af forbrændinger.A total of 245patients with suspected or known cyanide-poisoning were included in the clinical studies of the efficacy of hydroxocobalamin as an antidote.
I alt blev 245 patienter med formodet ellerkendt cyanidforgiftning inkluderet i de kliniske undersøgelser, hvor effekten af hydroxocobalamin som antidot blev undersøgt.In cyanide-poisoned patients, hydroxocobalamin is expected to bind cyanide to form cyanocobalamin, which is excreted in the urine.
Hos de cyanidforgiftede patienter forventes hydroxocobalamin at binde cyanid og danne cyanocobalamin, der herefter udskilles i urinen.Furthermore, in 34 patients with known cyanide concentrations above the lethal threshold(≥ 100 µmol/ l), 21(62%) survived following treatment with hydroxocobalamin.
Derudover var der blandt 34 patienter med en kendt cyanid- koncentration, der lå over den dødelige grænse(≥ 100 µmol/ l), 21(62%) der overlevede efter behandling med hydroxocobalamin.Each hydroxocobalamin molecule can bind one cyanide ion by substituting the hydroxo ligand linked to the trivalent cobalt ion to form cyanocobalamin.
Hvert hydroxocobalamin- molekyle kan binde en cyanid- ion ved at erstatte hydroxo- liganden, der er bundet til den trivalente kobolt- ion, og danne cyanocobalamin.Survival at hour 4 and at day 14 was significantly greater in 75 mg/ kg and150 mg/ kg hydroxocobalamin dose groups compared with dogs receiving sodium chloride 9 mg/ ml alone.
Overlevelsesraten efter 4 timer og efter 14 dage var væsentlighøjere i de dosisgrupper, der fik hydroxocobalamin 75 mg/ kg og 150 mg/ kg, sammenlignet med de hunde, der kun fik natriumklorid 9 mg/ ml.Because of its deep red colour, hydroxocobalamin has the potential to interfere with determination of laboratory parameters e. g. clinical chemistry, haematology, coagulation, and urine parameters.
Da hydroxocobalamin er mørkerødt, kan det medføre en interferens i forbindelse med bestemmelse af laboratorieparametre f. eks. klinisk kemi, hæmatologi, koagulation og urinparametre.While determination of blood cyanide concentration is not required andmust not delay treatment with hydroxocobalamin, it may be useful for documenting cyanide poisoning.
Selvom det ikke er påkrævet at påvise cyanidkoncentrationen i blodet, ogdette på ingen måde må føre til, at behandlingen med hydroxocobalamin udsættes, kan det være nyttigt til at dokumentere en cyanidforgiftning.Hydroxocobalamin reduced whole blood cyanide concentrations from about 120 nmol/ ml to 30-40 nmol/ ml by the end of the infusion compared with 70 nmol/ ml in dogs receiving sodium chloride 9 mg/ ml alone.
Hydroxocobalamin reducerede alle cyanidkoncentrationerne i blodet fra omkring 120 nmol/ ml til 30- 40 nmol/ ml hen mod afslutningen af infusionen, sammenlignet med 70 nmol/ ml hos de hunde, der kun fik natriumklorid 9 mg/ ml.The incidence of brain lesions was markedly lower in dogs having received 150 mg/ kg hydroxocobalamin than in dogs having received 75 mg/ kg hydroxocobalamin or sodium chloride 9 mg/ ml.
Incidensen af hjernelæsioner var markant lavere hos de hunde, der fik 150 mg/ kg hydroxocobalamin sammenlignet med de hunde, der fik 75 mg/ kg hydroxocobalamin eller 9 mg/ ml natriumklorid.Based on in vitro studies and pharmacokinetic data obtained in healthy volunteers the following table describes interference with laboratory tests that may be observed following a 5 g dose of hydroxocobalamin.
I følgende tabel beskrives, på baggrund af in vitro- undersøgelser og farmakokinetiske data fra raske frivillige, den interferens med laboratorieprøver, der muligvis kan observeres efter en hydroxocobalamin- dosis på 5 g.
