Eksempler på brug af Rasagiline på Engelsk og deres oversættelser til Dansk
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AZILECT 1 mg tablets rasagiline.
The metabolism of rasagiline proceeds through two main pathways.
What are the side effects of Azilect(Rasagiline Mesylate)?
Rasagiline pharmacokinetics are linear with dose over the range of 0.5-2 mg.
How should I use Azilect(Rasagiline Mesylate)?
Rasagiline produced statistically significant benefit compared to placebo.
Each tablet contains 1 mg rasagiline as mesilate.
AZILECT is a medicine containing the active ingredient rasagiline.
It is not known whether rasagiline is excreted in human milk.
Azilect(Rasagiline Mesylate) is used to treat the symptoms of Parkinson's disease.
What are the side effects of Azilect(Rasagiline Mesylate)?
Rasagiline is contraindicated in patients with severe hepatic insufficiency.
The active substance in AZILECT, rasagiline, is a monoamine oxidase-B inhibitor.
Rasagiline use in patients with moderate hepatic impairment should be avoided.
If you are allergic(hypersensitive) to rasagiline or any of the other ingredients of AZILECT.
Rasagiline undergoes almost complete biotransformation in the liver prior to excretion.
Thus, potent CYP1A2 inhibitors may alter rasagiline plasma levels and should be administered with caution.
At least five weeks should elapse between discontinuation of fluoxetine and initiation of treatment with rasagiline.
Experimental data indicated that rasagiline inhibits prolactin secretion and, thus, may inhibit lactation.
In parentheses is the adverse reaction incidence(% of patients) in rasagiline vs. placebo, respectively.
Co-administration of rasagiline and ciprofloxacin(an inhibitor of CYP1A2) increased the AUC of rasagiline by 83.
Caution should be used when initiating treatment with rasagiline in patients with mild hepatic insufficiency.
In post marketing experience these symptoms have also been observed in Parkinson's disease patients treated with rasagiline.
In the rasagiline clinical program overall 1361 patients were treated with rasagiline for 3076.4 patient years.
At least 14 days should elapse between discontinuation of rasagiline and initiation of treatment with fluoxetine or fluvoxamine.
Rasagiline did not present genotoxic potential in vivo and in several in vitro systems using bacteria or hepatocytes.
At least 14 days should elapse between discontinuation of rasagiline and initiation of treatment with MAO inhibitors or pethidine.
During the clinical development programme the occurrence of cases of melanoma prompted the consideration of a possible association with rasagiline.
There was also a statistically significant improvement over placebo with the rasagiline 0.5 mg group, yet the magnitude of improvement was lower.
These results indicate that rasagiline' s therapeutic concentrations are unlikely to cause any clinically significant interference with substrates of these enzymes.