Exemplos de uso de Cold ischemia time em Inglês e suas traduções para o Português
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The cold ischemia time was higher in group with conduits 11 versus 9 h; p 0.0008.
This finding may suggest that immunoinflammatory alterations associated with death and cold ischemia time may be predictive of a worse outcome.
On the other hand the cold ischemia time and HLA incompatibilities did not present any significance.
Clinical studies using various criteria, including PRA, number of HLA incompatibilities,donor characteristics, cold ischemia time and the presence of specific antibodies against donor.
The mean cold ischemia time was almost one hour higher on the recipients with PKF 23.6 vs. 22.7 hours, p 0.028.
Reactivity panel score, higher donor age,longer cold ischemia time, presence of urological complications, and CMV infection.
Cold ischemia time was 1 hour and 36 minutes and warm ischemia time was 3 minutes and 55 seconds.
Reported non-immunologic risk factors are donor age, cold ischemia time, gender mismatch, gender, weight, ethnicity, and medical status.11.
Prolonged cold ischemia time has also been associated with a worse kidney graft function and a higher incidence of DGF.
Our cases had a higher mean PVR 737 dynes/sec/cm5. This can be explained by the longer cold ischemia time in our sample 10 hours vs 7 hours in the study of Wierup et al.
Cold ischemia time, immunosuppressive therapies induction and maintenance, and episodes of acute rejection were not different between groups.
In our report,the main graft-related risk factors associated with DGF were cold ischemia time, out-of-state kidneys, and the need for a pre-implantation biopsy.
The cold ischemia time was not a predictor of mortality, demonstrating that the solution used provided adequate protection and not compromising the operative or late outcomes.
Therefore, based on this study,we need to install measures to reduce cold ischemia time up to 24 hours and decrease levels of serum creatinine to normal limits.
Therefore, the decision on the routine preimplantation biopsy performance should be cautious, since it can delay the process,increasing cold ischemia time.
Clinical criteria that may contribute to the outcome, such as donor age,HLA compatibility, cold ischemia time, delayed graft function and episodes of rejection were also analyzed.
Since a short cold ischemia time is crucial to ECD transplants success, it is possible that Brazilian allocation model based on HLA compatibility are not ideal for these transplants.
The preimplantation biopsy revealed findings consistent with acute tubular necrosis, and both kidneys were implanted inpatients aged 55 and 59 years, with cold ischemia times of about 12 and 18 hours, respectively.
Combined anesthesia technique, dialysis for more than 60 months,basiliximab, and cold ischemia time> 12 hours are risk factor for DGF, while liberal fluid regimens and kidneys from living donors are protective factors.
The third most often mentioned reason for exclusion of lungs for transplant was the distance between the place of death of the donor and the place where the transplant team was located,since it would increase cold ischemia time.
This solution would preserve the liver for a period up to three times greater than that of the previous solutions by passing the cold ischemia time of eight to 24 h without affecting significantly the organ viability.
However, graft survival depends on varied factors:graft age, cold ischemia time, occurrence of rejections, adherence to treatment, immunosuppressive drugs, compatibility, donor type, recipient disease, others.
Among the various conditions studied that show significant association with the risk of developing infectious episodes after kidney transplantation,we highlight those related to cold ischemia time on the graft and the immune factors7,21.
Donor/recipient HLA Human Leukocyte Antigen disparity, the basis of alloreactivity and acute rejection, is a major risk factor; donor age,graft cold ischemia time, the number of acute rejection episodes, hyperlipoproteinemia, hypertension, and CMV infection episodes have also been established as factors in the progression of chronic allograft dysfunction reviewed in detail in.
After logistic regression analysis with multiple variables, we observed a progressive increase in the risk of developing PKF from age greater than 40 years,with arterial hypertension and cold ischemia times greater than 36 hours Table 6.
This requires the adoption of appropriate strategies before, during, and after the transplantation procedure,which include the reduction of cold ischemia times; careful recipient selection; adequate immunosuppression therapy; improved graft selection based on histological criteria, vascular status and degree of glomerulosclerosis; and, in some cases, placing both donor kidneys in the same recipient.
The incidence of DGF was 69.3% and it was independently associated with donor's final serum creatinine and age, cold ischemia time, use of antibody induction therapy and recipient's diabetes mellitus.
In short term, the implementation of protocols to reduce cold ischemia time on the organ and proper preservation would be possible; review of protocols and screening of deceased donors to detect serological conditions and body integrity; strict adherence with the existing protocols for prevention and control of multidrug-resistant bacteria in order to reduce morbidity and mortality related to infection in this patient population.
Giral et al. demonstrated that DGF lasting for more than six days was correlated with decreased graft survival, andthat adrenaline administration, cold ischemia times over 16 hours, and recipient age above 55 years were associated with prolonged DGF.
Besides hypernatremia, there are other factors related to the potential donor which affect the quality of organs for transplantations, such as: age, history of alcohol consumption, smoking, cause of brain death,time of cold ischemia time the organ remains outside the donor's body in cooled conditions more than 12 hours,time of warm ischemia time between the start of anastomosis of the vena cava and reperfusion of the vena porta in liver receivers more than 45 minutes.