Exemplos de uso de Expanded criteria em Inglês e suas traduções para o Português
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Seventeen percent of the donors were expanded criteria donors.
All the donors with expanded criteria had at least one organ harvested.
One third of the recipients were grafted with kidneys from expanded criteria donors(ECD).6.
All the deceased donors with expanded criteria in the study were submitted to biopsy with transoperative freezing to evaluate organ viability.
These donors, selected less strictly, are called marginal,borderline or with expanded criteria.
Comparative study between kidney transplantation with deceased donor expanded criteria and donor standard criteria in a single center in Brazil.
Different algorithms based on histological parameters have been proposed to evaluate kidneys from expanded criteria donors.
Biopsies of expanded criteria donors were sampled as a wedge and submitted to transoperative freeze test to evaluate organ viability.
However, 75% of the standard criteria donors and 50% of the expanded criteria donors were males p 0.015.
However, several other authors have shown excellent results, from the oncologic point of view,on transplantations done with expanded criteria.
This study is an analysis of biopsies from deceased donors with expanded criteria, ideal deceased donors and live donors.
The use of donors with expanded criteria, however, arouses an important ethical dilemma, because these organs can increase the chance of transplantation failure.
Organs from donors with elevated terminal creatinine,whether standard or donors with expanded criteria, have a greater chance of being discarded.
Kayler et al., in a multivariate analysis,found that moderate arteriosclerosis was a significant predictor of the transplantation outcome in donors with and without expanded criteria.
The donors were also subdivided into live,ideal deceased and expanded criteria deceased. Donor age was stratified as below and higher or equal to 60 years.
Twenty-seven biopsies were from live donors, forty-seven from ideal deceased donors and thirty-six from donors with expanded criteria according to UNOS.
Therefore, this study detected the harvest of organs andtissues from donors with expanded criteria and identified flaws in the hemodynamic and physiological maintenance of these patients.
Age, serum creatinine and hypertension in deceased donors are characteristics that make up the definition of expanded criteria donor.
In terms of function, expanded criteria donors are individuals aged 60 years or older or subjects aged 50-59 years with at least two of three additional risk factors.
Donors were predominantly young adults median age 45 years who died of cerebrovascular disease 63.5% and 11.7% expanded criteria donors ECD.
The use of borderline or expanded criteria donors is a global trend to face the severe shortage of organs and the proven superiority of transplants with these donors against dialysis.
PKF incidence in this population was 55.2%; analyzing only the group of kidney recipients of expanded criteria donor, 70.9% had DGF.
Expanded criteria donors account for a considerable portion of transplant procedures and have been instrumental in increasing the supply of kidneys in the short term.
Because of the disproportion between supply and demand for kidneys for transplantation,the use of expanded criteria donors ECD significantly increased over the past years.
The study population consists of 110 kidney transplant recipients subdivided into 27 from live donors, 47 from deceased donors considered ideal, and36 from deceased donors with expanded criteria.
The question still persists as to whether using expanded criteria donor kidneys- an option deemed safe in the short term- to increase the supply of organs and reduce transplant waiting times is a valid option.
The study enrolled 255 renal transplant recipients; 231 90.6% were given deceased donor kidneys from standard criteria donors and24 9.4% received deceased donor kidneys from expanded criteria donors; all were first-time recipients.
To receive a kidney from a deceased donor with expanded criteria is associated with a 70% increase in the risk of graft loss, and the higher incidence of DGF, compared to deceased donor transplants that do not meet this classification.
Over this period, was expanded the indication for resection to patients with metastases in both hepatic lobes, patients undergoing salvage chemotherapy post-treatment, cases of tumors in cirrhotic livers and cases of marginally resectable tumors. Thus,these patients presented the expanded criteria that were the objective of this study.
These outcomes confirm the safety of using expanded criteria donors as a viable option to increase the supply of organs for donation and provide recipients with good functional outcomes and increased survival.