Exemplos de uso de To exercise intolerance em Inglês e suas traduções para o Português
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Of symptoms and to exercise intolerance, progressively reducing FC. 7.
In fact, the weakness of inspiratory muscle often observed in patients with HF may be related to exercise intolerance.
The mechanisms related to exercise intolerance in patients with heart failure have not been fully defined.
Heart failure(hf)-induced skeletal muscle atrophy is often associated to exercise intolerance and poor prognosis.
This can lead to exercise intolerance(inability to carry out physical activity), difficulty breathing and fluid retention.
The patients with respiratory problems presented muscular dysfunction,which contributes to exercise intolerance, dyspnea and hypercapnea.
These factors lead to exercise intolerance and progressive worsening of physical condition to the point of limiting daily life activities.
In patients with COPD, such changes have been shown to be related to exercise intolerance, impaired quality of life, and increased mortality.
Such factors lead to exercise intolerance and progressive worsening of physical fitness,to the point of limiting activities of daily living ADL.
The central and peripheral chemoreflex and the ergoreflex are involved in hyperventilation at rest and during exercise, contributing to exercise intolerance.
Respiratory muscle function impairment contributes to exercise intolerance, dyspnea, and hypercapnia; however, it can be improved with adequate physical training.
Heart failure(hf) is associated with a derangement of muscle architecture and metabolism,directly contributing to exercise intolerance, weakness and mortality.
These factors lead to exercise intolerance and progressive decrease of physical fitness, even limiting DLA, and possibly causing social isolation, anxiety, depression and dependence.
Alterations on the neuro-immune-endocrine axis andmetabolic abnormalities on the muscle-skeletal have been proposed in order to explain alterations that lead to exercise intolerance as well as possible mediators of their beneficial effects.
A reduction in lean mass leads to exercise intolerance, which has been described as an essential factor for impairing quality of life, increasing the frequency of exacerbations/hospital admissions, and increasing mortality.
Thus, the reduction of the inspiratory muscle strength can aggravate the exacerbation of chemoreflex sensitivity in patients with HF,which could potentially be related to reductions in functional capacity and to exercise intolerance.
In a review of the metabolic factors related to exercise intolerance in patients with HF, Wassermann et al. suggest the occurrence of mitochondrial changes in the activity of cytochrome c oxidase, creatine kinase, and other oxidative enzymes, as well as remodeling of the fast-contracting fibers at the expense of low-contracting fibers.
In addition to affecting the lungs, COPD is also accompanied by systemic manifestations that have a serious impact on the quality of life and survival of patients, including nutritional depletion and skeletal muscle dysfunction,which contribute to exercise intolerance.
Therefore, alterations in the cardiac relaxation, the presence of myocardial hypertrophy and remodeling are key abnormalities that alter the ventricular rigidity and the filling pressures,leading to exercise intolerance, which would be the first symptom of HFNEF and a determinant factor in the decrease of quality of life.
It means that patients with HF are more susceptible to exercise intolerance due to the effects of the metaboreflex activation by the inspiratory muscles work, so that the inspiratory muscle training attenuates the inspiratory metaboreflex in patients with HF and with the inspiratory muscles weakness Figure 5.
However, changes in cardiac relaxation, the presence of myocardial hypertrophy, and remodeling are key defects that change the ventricular stiffness and filling pressures,thus leading to exercise intolerance, which would be the first symptom of HFNEF and the first determinant of reduced quality of life.
After heart transplantation,patients present physical exercise intolerance due to disturbance on hemodynamic performance as result of cardiac, neurohormonal, vascular, muscle-skeletal and pulmonary abnormalities.
Intolerance to exercise due to breathing difficulties may also be apparent.
Class II patients usually exhibit coughing and unusual intolerance to exercise.