Oestrogen is essential for healthy bone formation, healthy gene expression, maintaining healthy cholesterol levels and is vital for a healthy menstrual cycle.
如果DNA能够修复,那么p53基因就会允许细胞分裂继续发生,以确保正常的基因表达。
If the DNA is capable of repair, the p53 gene allows cellular division to continue occurring,ensuring the proper genetic expression.
Rather than evaluating a single gene, multiparameter gene expression tests analyze the RNA of multiple genes in a tumor at the same time.
几乎所有活细胞的荧光成像方法基于荧光蛋白的基因表达。
Almost all of the fluorescent imagingmethods in living cells are based on genetic expression of fluorescent proteins.
该小组研究了蛋白质触发途径的基因表达谱,然后还审查了麻风患者单核细胞如何回应NOD2的。
The team studied the gene expression profiles of the protein-triggered pathways and then also examined how the monocytes of leprosy patients responded to NOD2.
For the current study,lead author Sean Silverman and team assessed the genetic expression of the complement system in a mouse model of retinitis pigmentosa.
在所有细胞类型中,衰老的成纤维细胞显示出最显着的差异基因表达,RNA动态增强和网络熵。
Among all cell types,aged fibroblasts showed most significant differential gene expression, increased RNA dynamics, and network entropy.
In April, Yale University stem cell biologist Alejandro De LosAngeles reported that the technique prompted similar gene expression changes in human IPS cells.
Zylka的团队使用计算机程序推断出哪些化学物质引起的基因表达变化彼此相似。
Zylka's team then usedcomputer programs to deduce which chemicals caused gene expression changes that were similar to each other.
Using a single reference genome,the researchers trained the program to understand how DNA controls gene expression across more than 200 different tissues and cell types.
直到最近,实验技术还没有精确测量逃避失活的基因表达率所需的灵敏度。
Until recently, experimental techniques did nothave the sensitivity needed to precisely measure the gene expression rates that escape inactivation.
具体来说,科学家们寻找了非整倍体细胞之间共享的基因表达变化,尽管它们的染色体拷贝数不同。
Specifically, the scientists looked for gene expression changes that were shared among the aneuploid cells despite their differences in chromosome copy number.
这项新的研究表明,发育中的神经干细胞在不同的时间点具有特定的基因表达(转录)程序。
The new study presents evidence that developing neuralstem cells are equipped with specific gene expression(transcriptional) programs at different points in time.
肠道细菌分泌的一氧化氮结合到成千上万的宿主蛋白上,从而完全改变了线虫调节它的自身基因表达的能力。
Nitric oxide secreted by gut bacteria attached to thousands of host proteins,completely changing a worm's ability to regulate its own gene expression.
最后,从早期胚胎外的植体可以用于确定控制第一阶段的胚胎发育的基因表达的机制。
Finally, explants from early embryos canbe used to determine the mechanisms controlling gene expression during the first stages of embryogenesis.
其他饮食,包括那些富含食糖的饮食,都没有导致显著的体重增加或相同方式的基因表达改变。
None of the other diets, including those rich in sugar,led to significant weight gain or changed gene expression in the same way.
他们还利用尖端技术分析斑块中所有个体免疫细胞的基因表达,以研究其功能。
They also used cutting-edge technologies to analyze gene expression in all the individual immune cells in the plaque to study their function.
更重要的是,一个转录因子通常靶向细胞中数千个基因组位置并改变每个位置的基因表达。
What's more, one transcription factor typically targets thousands of genomic locations in the cell andchanges gene expression at each location.
为了用数以千计的基因表达谱扩大资源,该研究小组将单细胞基因组学数据重新定位到原有的图谱。
To augment the resource with thousands of genes expression profiles, the team back-mapped single-cell genomics data to the original atlas.
相比之下,来自女性患者的脑细胞显示出阿尔茨海默病中更严重的基因表达变化,以及一系列改变。
By contrast, brain cells from femalepatients showed dramatically more severe gene-expression changes in Alzheimer's disease, and an expanded set of altered pathways.
相反,如果哪个患者的基因表达非常低,他可能会存活更长时间并且预后良好。
Conversely, if that patient has a very low expression of those genes, he's probably going to survive longer and have a good prognosis.".
这些不同的亚型具有不同的基因表达模式和不同的平均患者预后。
These subtypes have different patterns of gene expression and different average patient outcomes.
通过创造不同样式的基因表达,格斯巴赫希望这一系统可以被用于组织工程学。
And by creating different patterns of gene expression, Gersbach hopes the system can be used in tissue engineering.
发现与健康组织相关的基因表达得到了实质性的恢复,并且朝着未来治疗方法的发展迈出了有希望的一步。
They noted a substantial restoration of gene expression associated with healthy tissue, a promising step toward the development of future therapies.
直到最近,发现癌症组织的基因表达模式一直是使用整个肿瘤组织进行的,这一过程被称为批量测序。
Until recently, finding patterns of gene expression for cancer tissue has been performed using whole tumor tissue, a process called bulk sequencing.
已经知道由microRNA调控的基因表达对于防止癌细胞的扩散很重要。
The regulation of gene expression by microRNAs is known to be important in preventing the spread of cancer cells.
Global reprogramming of gene expression to deal with stressful situations and high levels of DNA damage requires loosening the interaction of DNA with chromatin proteins.
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