What is the translation of " HYDROXYLERING " in English?

• hydroxylation

Examples of using Hydroxylering in Danish and their translations into English

Yderligere hydroxylering forekommer før elimination.
Further hydroxylation occurs prior to elimination.

Biotransformationer i katte sker ved hydroxylering i leveren.
Biotransformations in the cat occur by hydroxylation in the liver.

En blev opnået ved hydroxylering af pyrrolidonringen(1, 6% af dosis) og den anden ved åbning af pyrrolidonringen 0, 9% af dosis.
One was obtained by hydroxylation of the pyrrolidone ring(1.6% of the dose) and the other one by opening of the pyrrolidone ring 0.9% of the dose.

Doxazosin metaboliseres primært ved O- demetylering og hydroxylering.
Doxazosin is primarily metabolised by O-demethylation and hydroxylation.

Celecoxib metaboliseres i leveren ved hydroxylering, oxidation og til dels glucuronidation.
Celecoxib is metabolised in the liver by hydroxylation, oxidation and some glucuronidation.

Doxazosin bliver primært metaboliseret ved O- demethylering og hydroxylering.
Doxazosin is primarily metabolised by O-demethylation and hydroxylation.

Cholecalciferol omdannes i leveren ved hydroxylering til den aktive form 25- hydroxycholecalciferol.
Cholecalciferol is converted in the liver by hydroxylation to the active form 25- hydroxycholecalciferol.

Biotransformation De vigtigste metaboliseringsveje hos raske forsøgspersoner er oxidering og hydroxylering.
Biotransformation Main metabolic pathways identified in healthy subjects are oxidation and hydroxylation.

Væsentlige biotransformationer hos hunde inkluderer hydroxylering, konjugering med glukoronsyre og N- methylering i leveren.
Major biotransformations in the dog include hydroxylation, glucuronic acid conjugation and N-methylation in the liver.

MPTP toksicitet sandsynligvis kommer fra den generation af reaktive ilt arter gennem tyrosin hydroxylering.
MPTP's toxicity likely comes from the generation of reactive oxygen species through tyrosine hydroxylation.

Metabolismen sker primært gennem N- demetylering og hydroxylering, efterfulgt af konjugation med sulfat og glukoronsyre.
The major routes of metabolism are N-demethylation and hydroxylation, followed by conjugation with sulphate and glucuronic acid.

Aripiprazol metaboliseres hovedsageligt i leveren via tre biotransformationsveje: dehydrogenering, hydroxylering og N- dealkylering.
Aripiprazole is extensively metabolised by the liver primarily by three biotransformation pathways: dehydrogenation, hydroxylation, and N-dealkylation.

Selvom micafungin er et substrat for CYP3A in vitro, er hydroxylering af CYP3A ikke en større metaboliseringsbane for micafungin in vivo.
Even though micafungin is a substrate for CYP3A in vitro, hydroxylation by CYP3A is not a major pathway for micafungin metabolism in vivo.

O- demetylering af en eller begge sidekæder, efterfulgt af oxidering til carboxylsyre; 2 oxidering af acetylengruppen efterfulgt af hydrolyse til arylcarboxylsyre; og 3 aromatisk hydroxylering af phenyl- acetylengruppen.
O-demethylation of either side chain or both, followed by oxidation to the carboxylic acids; 2 oxidation of the acetylene moiety followed by hydrolysis to the aryl carboxylic acid; and 3 aromatic hydroxylation of the phenyl-acetylene moiety.

Af disse er M- 1(katekolform), M- 2(metoxyform af M- 1) og M- 5(hydroxylering ved sidekæde) set i den systemiske cirkulation af micafungin.
Micafungin has been shown to be metabolised to several compounds; of these M-1(catechol form), M-2(methoxy form of M-1) and M-5(hydroxylation at the side chain) of micafungin have been detected in systemic circulation.

Den hastighedsbegrænsende trin i konverteringen til tryptophan til serotonin er hydroxylering af tryptophan til 5htp.
The rate-limiting step in the conversion to Tryptophan to Serotonin is the hydroxylation of Tryptophan to 5HTP.

Biotransformation D3- vitamin metaboliseres hurtigt ved hydroxylering i leveren til 25- hydroxyvitamin D3 og metaboliseres efterfølgende i nyrerne til 1, 25- dihydroxyvitamin D3, som repræsenterer den biologisk aktive form.
Biotransformation Vitamin D3 is rapidly metabolized by hydroxylation in the liver to 25-hydroxyvitamin D3, and subsequently metabolized in the kidney to 1,25-dihydroxyvitamin D3, which represents the biologically active form.

Pioglitazon gennemgår en omfattende metabolisme i leveren ved hydroxylering af alifatiske methylengrupper.
Pioglitazone undergoes extensive hepatic metabolism by hydroxylation of aliphatic methylene groups.

Den hastighedsbegrænsende trin i konverteringen til tryptophan til serotonin er hydroxylering af tryptophan til 5htp. Supplering direkte med 5HTP stedet Tryptofan menes at være den mest effektive måde at øge hjernens serotonin. Nogle undersøgelser har også vist, at 5HTP kan nedsætte appetitten, kalorieindtag, og vægten hos overvægtige individer.
The rate-limiting step in the conversion to Tryptophan to Serotonin is the hydroxylation of Tryptophan to 5HTP. Supplementing directly with 5HTP rather than Tryptophan is believed to be the most efficient way to increase brain Serotonin. Some studies have also shown that 5HTP may reduce appetite, caloric intake, and weight in obese individuals.

Baseret på in vitro- forsøg er CYP3A4 og CYP2D6 ansvarlige for dehydrogenering og hydroxylering af aripiprazol, og N- dealkylering katalyseres ved CYP3A4.
Based on in vitro studies, CYP3A4 and CYP2D6 enzymes are responsible for dehydrogenation and hydroxylation of aripiprazole, and N-dealkylation is catalysed by CYP3A4.

Der er identificeret fem metaboliske pathways for lasofoxifen: direkte glucuronidation; direkte sulfonering; hydroxylering af phenyltetralin- delen(med efterfølgende konjugerende metabolisme af catechol- intermediaterne ved metylering og glucuronidation); oxidering af pyrrolidinringen; og phenylhydroxylering.
Five metabolic pathways of lasofoxifene have been identified: direct glucuronidation; direct sulfation; hydroxylation at the phenyl tetraline moiety(with subsequent conjugative metabolism of the catechol intermediates by methylation and glucuronidation); oxidation at the pyrrolidine ring; and phenyl hydroxylation..

Der er identificeret fire metaboliske processer in vivo, hvoraf ingen udgjorde mere end 6, 5% af dosis, nemlig dealkylering, hydroxylering, dehydrogenering og benzisoxazolspaltning.
Four metabolic pathways have been identified in vivo, none of which accounted for more than 6.5% of the dose: dealkylation, hydroxylation, dehydrogenation, and benzisoxazole scission.

Derefter gennemgår amfenac en omfattende metabolisme til mere polære metabolitter, der involverer hydroxylering af den aromatiske ring, som fører til dannelse af glukuronidkonjugat.
Subsequently, amfenac undergoes extensive metabolism to more polar metabolites involving hydroxylation of the aromatic ring leading to glucuronide conjugate formation.

Derudover methyleres stoffet af COMT til 3- O- methyltolcapon og metaboliseres af cytochrom P450 3A4 og P450 2A6 til en primær alkohol(hydroxylering af methylgruppen), som derefter oxideres til carboxylsyren.
In addition, the compound is methylated by COMT to 3-O-methyl-tolcapone and metabolised by cytochromes P450 3A4 and P450 2A6 to a primary alcohol(hydroxylation of the methyl group), which is subsequently oxidised to the carboxylic acid.

Ud over den aktive metabolit dannes inaktive metabolitter, herunder 2 hovedmetabolitter dannet ved hydroxylering af butylsidekæden og en metabolit af mindre betydning, en N- 2- tetrazolglucuronid.
In addition to the active metabolite, inactive metabolites are formed, including two major metabolites formed by hydroxylation of the butyl side chain and a minor metabolite, an N-2 tetrazole glucuronide.

Biotransformation Der er fundet 7 hovedmetabolitter og de metaboliske veje er vist at være glukoronidering ved pyridin- nitrogenatomet, pyridin- N- oxidation med og uden 3'- hydroxylering på indanringen, 3'- hydroxylering af indan, p- hydroxylering af phenylmethylgruppen, og N- depyridomethylering med og uden 3'- hydroxylering..
Biotransformation Seven major metabolites were identified and the metabolic pathways were identified as glucuronidation at the pyridine nitrogen, pyridine- N- oxidation with and without 3'- hydroxylation on the indane ring, 3'- hydroxylation of indane, p- hydroxylation of phenylmethyl moiety, and N- depyridomethylation with and without the 3'- hydroxylation..

How to use "hydroxylering" in a Danish sentence

Magic syre katalyserer også elektrofil hydroxylering af aromatiske forbindelser med hydrogenperoxid, hvilket resulterer i fremstilling med højt udbytte af monohydroxylerede produkter.

Ibuprofen metaboliseres i leveren hovedsageligt ved hydroxylering og carboxylering af isobutylgruppen.

Hydroxyproline er hydroxylering af prolin, og det afhænger af vitamin C.

I betragtning af behandlingsvirkningens størrelsesorden sammenlignet med den store placebovirkning og de uklare virkninger med hensyn til psykosociale funktioner er den dehydrogenering, hydroxylering og N-dealkylering.

Under iltfattige forhold vil hydroxylering hæmmes, hvorved HIF-1a ophobes.

Fra progesteron, 21-β-hydroxylase tilvejebringer 11-hydroxylering af deoxycorticosteron ved methylgruppe i stilling 21.

Afobazole undergår effekten af ​​den første passage gennem leveren, de vigtigste retninger af metabolisme er hydroxylering på den aromatiske ring af benzimidazolcyklusen og oxidation på morpholinfragmentet.

Ethinylestradiol metaboliseres primært ved aromatisk hydroxylering, men der dannes en lang række hydroxylerede og methylerede metabolitter, og disse findes som frie metabolitter og som glukuronid- og sulfatkonjugater.

D-hydroxylering af vitamin D i nyrerne øges, hvilket resulterer i en stigning i niveauet af dets aktive form (calcitriol), som er involveret i produktionen af ​​et protein, der tilvejebringer calciumabsorption.

How to use "hydroxylation" in an English sentence

Haloperidol disposition is dependent on debrisoquine hydroxylation phenotype .

Mutant debrisoquine hydroxylation genes in Parkinson’s disease.

Optimal translational termination requires C4 lysyl hydroxylation of eRF1.

PubMed:Stereo- and regioselective hydroxylation of alpha-ionone by Streptomyces strains.

Consequences of lysine hydroxylation of non-histone proteins may be variable.

Impairment of phenylalanine hydroxylation in chronic renal insufficiency.

Hypersensitive radical probe studies of chloroperoxidase-catalyzed hydroxylation reactions.

Effective L-Tyrosine Hydroxylation by Native and Immobilized Tyrosinase.

Simplified Schematic Representation of L-tyrosine Hydroxylation by Tyrosinase.

Prokaryotic enzymes might catalyse hydroxylation of antibiotic peptides.